A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Participants Refractory to Conventional Therapy
Public ClinicalTrials.gov record NCT03905512. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Study to Compare the Efficacy of SEL-212 to KRYSTEXXA® in Gout Patients Refractory to Conventional Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, parallel-arm, multicenter study to compare the safety and efficacy profiles of SEL-212 and KRYSTEXXA®. Participants will be randomized 1:1 to receive treatment with SEL-212 or KRYSTEXXA® for 6 months. Efficacy assessments, as measured by serum uric acid (SUA) levels, will be conducted at intervals that are appropriate to determine treatment effect differences. Safety will be monitored throughout the study.
Study identification
- NCT ID
- NCT03905512
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 170 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 21 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 7, 2019 (Actual)
- Primary completion
- Aug 5, 2020 (Actual)
- Completion
- Aug 5, 2020 (Actual)
- Last update posted
- Oct 17, 2023
2019 – 2020
United States locations
- U.S. sites
- 43
- U.S. states
- 21
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group, LLC | Anniston | Alabama | 36207 | — |
| Arizona Arthritis & Rheumatology Research, PLLC | Sun City | Arizona | 85351 | — |
| Baptist Health Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| Medvin Clinical Research | Covina | California | 91722 | — |
| Valerius Medical Group and Research Center of Greater Long Beach, Inc. | Los Alamitos | California | 90720 | — |
| Arthritis Care and Research Center | Poway | California | 92064 | — |
| MD Strategies Research Centers | San Diego | California | 92119 | — |
| Clinical Research of West Florida | Clearwater | Florida | 33765 | — |
| QPS-Medical Research Assoc LLC | Miami | Florida | 33143 | — |
| Well Pharma Medical Research Corp. | Miami | Florida | 33143 | — |
| Panax Clinical Research | Miami Lakes | Florida | 33014 | — |
| Accelerated Enrollment Solutions (AES) | Orlando | Florida | 32806 | — |
| Rheumatology Associates of Central Florida, PA | Orlando | Florida | 32806 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33603 | — |
| Advent Health Group Multispecialty at Habana and Bruce B. Downs | Tampa | Florida | 33614 | — |
| Arthritis Center of North Georgia | Gainesville | Georgia | 30501 | — |
| Better Health Clinical Research, Inc. | Newnan | Georgia | 30265 | — |
| Institute of Arthritis Research | Idaho Falls | Idaho | 83404 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Klein & Associates, M.D., P.A. | Cumberland | Maryland | 21502 | — |
| Klein & Associates, M.D., P.A. | Hagerstown | Maryland | 21740 | — |
| The Center for Rheumatology and Bone Research | Wheaton | Maryland | 20902 | — |
| Clinical Pharmacology Study Group | Worcester | Massachusetts | 01605 | — |
| University Hospital | Ann Arbor | Michigan | 48109 | — |
| Elite Clinical Research, LLC | Jackson | Mississippi | 39202 | — |
| TEST | Blue Springs | Missouri | 64014 | — |
| NYU Langone Ambulatory Care Brooklyn Heights | Brooklyn | New York | 11201 | — |
| DJL Clinical Research | Charlotte | North Carolina | 28210 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Cape Fear Arthritis Care PLLC | Leland | North Carolina | 28451 | — |
| Cape Fear Arthritis Care PLLC | Leland | North Carolina | 28541 | — |
| New Horizons Clinical Research | Cincinnati | Ohio | 45242 | — |
| Arthritis & Rheumatology Center of Oklamhoma, PLLC | Oklahoma City | Oklahoma | 73102 | — |
| Altoona Center for Clinical Research | Duncansville | Pennsylvania | 16635 | — |
| Clinical Research Center of Reading, LLC | Wyomissing | Pennsylvania | 19610 | — |
| West Tennessee Research Institute, LLC | Jackson | Tennessee | 38305 | — |
| Amarillo Center for Clinical Research | Amarillo | Texas | 79124 | — |
| Austin Regional Clinic | Austin | Texas | 78731 | — |
| Tekton Research | Austin | Texas | 78745 | — |
| Metroplex Clinical Research Center | Dallas | Texas | 75231 | — |
| Pioneer Research Solutions, Inc. | Houston | Texas | 77099 | — |
| Southwest Rheumatology Research, LLC | Mesquite | Texas | 75150 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03905512, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 17, 2023 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03905512 live on ClinicalTrials.gov.