ClinicalTrials.gov record
A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCON
ClinicalTrials.gov ID: NCT03918447
Public ClinicalTrials.gov record NCT03918447. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Autosomal Dominant Polycystic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This international, multi-center, randomized, double-blind, placebo-controlled Phase 3 trial will study the safety, tolerability, and efficacy of bardoxolone methyl in qualified patients with ADPKD. Approximately 850 patients will be enrolled.
Study identification
- NCT ID
- NCT03918447
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 667 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 29, 2019 (Actual)
- Primary completion
- Aug 8, 2023 (Actual)
- Completion
- Aug 8, 2023 (Actual)
- Last update posted
- Jun 3, 2025
2019 – 2023
United States locations
- U.S. sites
- 83
- U.S. states
- 28
- U.S. cities
- 72
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Nephrology Associates PC | Homewood | Alabama | 35209 | — |
| Nephrology Consultants, LLC | Huntsville | Alabama | 35805 | — |
| AKDHC | Glendale | Arizona | 85306 | — |
| Aventiv Research, Inc | Mesa | Arizona | 85210 | — |
| University of Arizona | Tucson | Arizona | 85719 | — |
| Rancho Research Institute | Downey | California | 90242 | — |
| California Institute Renal Research | La Mesa | California | 91942 | — |
| University of California, Los Angeles | Los Angeles | California | 90025 | — |
| Keck USC/LAC | Los Angeles | California | 90033 | — |
| Amicis Research Center | Northridge | California | 91324 | — |
| Stanford University | Palo Alto | California | 94304 | — |
| Apex Research of Riverside | Riverside | California | 92505 | — |
| University of California San Francisco | San Francisco | California | 94143 | — |
| Western Nephrology | Arvada | Colorado | 80002 | — |
| University of Colorado Anschutz Medical Center | Aurora | Colorado | 80045 | — |
| Kidney Associates of Colorado | Denver | Colorado | 80210 | — |
| Denver Nephrologist, PC | Denver | Colorado | 80230 | — |
| Western Nephrology and Mineral Bone Disease, PC | Westminster | Colorado | 80031 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06520 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Pro-Care Research Center, Corp. | Miami Gardens | Florida | 33014 | — |
| Discovery Medical Research Group | Ocala | Florida | 34471 | — |
| Innovation Medical Research Center, Inc | Palmetto Bay | Florida | 33157 | — |
| Volunteer Medical Research | Port Charlotte | Florida | 33952 | — |
| University of South Florida | Tampa | Florida | 33606 | — |
| Florida Premier Research Institute, LLC | Winter Park | Florida | 32789 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Georgia Nephrology, LLC | Lawrenceville | Georgia | 30046 | — |
| Boise Kidney & Hypertension, PLLC | Caldwell | Idaho | 83605 | — |
| Boise Kidney & Hypertension, PLLC | Meridian | Idaho | 83642 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60617 | — |
| Loyola University Chicago | Maywood | Illinois | 60153 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66224 | — |
| Cotton O'Neil Clinical Research Center | Topeka | Kansas | 66606 | — |
| Ascension Via Christi Research | Wichita | Kansas | 67214 | — |
| Kansas Nephrology Research Institute, LLC | Wichita | Kansas | 67214 | — |
| Renal Associates of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Northwest Louisiana Nephrology | Shreveport | Louisiana | 71101 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| The Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| KidneyCare and Tranplant Services of New England | Springfield | Massachusetts | 01104 | — |
| Renal and Transplant Associates of New England, PC | Springfield | Massachusetts | 01107 | — |
| Paragon Health PC d/b/a Nephrology Center PC | Kalamazoo | Michigan | 49007 | — |
| Michigan Kidney Consultants | Pontiac | Michigan | 48341 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Clinical Research Consultants, LLC | Kansas City | Missouri | 64111 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| KSOSN | Las Vegas | Nevada | 89129 | — |
| Nephrology Associates, P.C. | Flushing | New York | 11355 | — |
| Division of Kidney Diseases and Hypertension | Great Neck | New York | 11021 | — |
| NYU Winthrop Hospital | Mineola | New York | 11501 | — |
| Mountain Kidney & Hypertension Associates | Asheville | North Carolina | 28801 | — |
| Metrolina Nephrology Associates | Charlotte | North Carolina | 28204 | — |
| North Carolina Nephrology, P.A. 2nd Floor | Raleigh | North Carolina | 27609 | — |
| Brookview Hills Research Associates, LLC | Winston-Salem | North Carolina | 27103 | — |
| Cincinnati VA Medical Center | Cincinnati | Ohio | 45220 | — |
| University of Cincinnati College of Medicine | Cincinnati | Ohio | 45267 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Remington-Davis Clinical Research | Columbus | Ohio | 43215 | — |
| Northeast Clinical Research Center | Bethlehem | Pennsylvania | 18017 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19014 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Columbia Nephrology Associates, PA | Columbia | South Carolina | 29203 | — |
| Nephrology Associates, P.C. | Nashville | Tennessee | 37205 | — |
| TTUHSC | Amarillo | Texas | 79106 | — |
| Arlington Nephrology, PA | Arlington | Texas | 76015 | — |
| Research Management, Inc. | Austin | Texas | 78751 | — |
| Research Management, Inc. | Austin | Texas | 78758 | — |
| Liberty Research Center | Dallas | Texas | 75230 | — |
| Renal Disease Research Institute | Dallas | Texas | 75235 | — |
| Davita Clinical Research | El Paso | Texas | 79925 | — |
| DaVita Med Center | Houston | Texas | 77004 | — |
| Clinical Advancement Center | San Antonio | Texas | 78215 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Nephrology Associates of Northern Virginia, Inc. | Fairfax | Virginia | 22033 | — |
| Swedish Medical Center | Seattle | Washington | 98052 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Milwaukee Nephrologists, SC | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03918447, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 3, 2025 · Synced Nov 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03918447 live on ClinicalTrials.gov.