ClinicalTrials.gov record
Trial of Parkinson's And Zoledronic Acid
ClinicalTrials.gov ID: NCT03924414
Public ClinicalTrials.gov record NCT03924414. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
TOPAZ: Trial of Parkinson's And Zoledronic Acid A Randomized Placebo-controlled Trial of Zoledronic Acid for the Prevention of Fractures in Patients With Parkinson's Disease
Study identification
- NCT ID
- NCT03924414
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- California Pacific Medical Center Research Institute
- Other
- Enrollment
- 2,721 participants
Conditions and interventions
Conditions
Interventions
- Zoledronic Acid 5Mg/Bag 100Ml Inj Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 14, 2019
- Primary completion
- Feb 27, 2026
- Completion
- Feb 27, 2026
- Last update posted
- Jun 24, 2026
2019 – 2026
United States locations
- U.S. sites
- 77
- U.S. states
- 28
- U.S. cities
- 61
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic | Scottsdale | Arizona | 85259 | — |
| Washington Regional Medical Center | Fayetteville | Arkansas | 72703 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Sutter Health | Berkeley | California | 94705 | — |
| Parkinson's and Movement Disorder Institute | Fountain Valley | California | 92708 | — |
| University of California, Irvine | Irvine | California | 92697 | — |
| Loma Linda University | Loma Linda | California | 92350 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| University of California, Los Angeles | Los Angeles | California | 90095 | — |
| Valley Parkinson Clinic | Los Gatos | California | 95032 | — |
| Parkinson's Disease and Movement Disorder Center of Silicon Valley | Palo Alto | California | 94301 | — |
| University of California, Riverside | Riverside | California | 92521 | — |
| Sutter Health | Sacramento | California | 95816 | — |
| University of California, Davis | Sacramento | California | 95816 | — |
| University of California, San Francisco | San Francisco | California | 94115 | — |
| University of Colorado, Denver | Aurora | Colorado | 80045 | — |
| St. Mary's Medical Center | Grand Junction | Colorado | 81501 | — |
| University of Connecticut | Farmington | Connecticut | 06030 | — |
| University of Connecticut | Farmington | Connecticut | 06032 | — |
| Hartford Healthcare | Hartford | Connecticut | 06103 | — |
| University of Florida | Gainesville | Florida | 32611 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Parkinson's Foundation | Miami | Florida | 33131 | — |
| University of Miami | Miami | Florida | 33146 | — |
| Morehouse School of Medicine | Atlanta | Georgia | 30310 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Queens Medical Center | Honolulu | Hawaii | 96813 | — |
| Northwestern Medicine | Chicago | Illinois | 60611 | — |
| Cook County Health & Hospitals System | Chicago | Illinois | 60612 | — |
| Rush University | Chicago | Illinois | 60612 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Loyola University | Chicago | Illinois | 60660 | — |
| Edward Hines, Jr. VA Hospital | Hines | Illinois | 60141 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University of Kentucky | Lexington | Kentucky | 40506 | — |
| Ochsner Health System | New Orleans | Louisiana | 70119 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Boston University | Boston | Massachusetts | 02215 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Quest Research Institute | Farmington Hills | Michigan | 48334 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03766 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Stony Brook University Medical Center | East Setauket | New York | 11733 | — |
| Northwell Health | Glen Cove | New York | 11542 | — |
| Northwell Health | Great Neck | New York | 11021 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| New York University Langone Health | New York | New York | 10017 | — |
| Mount Sinai Beth Israel | New York | New York | 10019 | — |
| Columbia University | New York | New York | 10032 | — |
| Weill Cornell Medicine | New York | New York | 10065 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| Stony Brook University Medical Center | Stony Brook | New York | 11794 | — |
| Duke University | Durham | North Carolina | 27708 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27109 | — |
| University of Cincinnati | Cincinnati | Ohio | 45219 | — |
| Case Western Reserve University, UH Cleveland | Cleveland | Ohio | 44106 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15260 | — |
| Lankenau Medical Center | Wynnewood | Pennsylvania | 19096 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Veracity Neuroscience LLC | Memphis | Tennessee | 38157 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37240 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| University of Texas Health Houston Medical Center | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84112 | — |
| University of Vermont | Burlington | Vermont | 05405 | — |
| Booth Gardner Parkinson's Care Center at EvergreenHealth | Kirkland | Washington | 98034 | — |
| University of Wisconsin | Madison | Wisconsin | 53706 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03924414, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 24, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03924414 live on ClinicalTrials.gov.