A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)
Public ClinicalTrials.gov record NCT03933202. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cladribine Tablets: Observational Evaluation of Effectiveness and PROs in Suboptimally Controlled Patients Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the effectiveness, safety and Patient-Reported Outcomes (PROs) of cladribine tablets in participants with RMS including relapsing-remitting multiple sclerosis (RRMS) and active secondary progressive multiple sclerosis (aSPMS), who transition to cladribine tablets after suboptimal response to any oral or infusion Disease-Modifying Drugs (DMDs) approved in the United States (US) for RMS in a real-world-setting.
Study identification
- NCT ID
- NCT03933202
- Recruitment status
- Completed
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 291 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 22, 2019 (Actual)
- Primary completion
- Nov 11, 2024 (Actual)
- Completion
- Nov 11, 2024 (Actual)
- Last update posted
- Jan 2, 2026
2019 – 2024
United States locations
- U.S. sites
- 66
- U.S. states
- 26
- U.S. cities
- 61
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Central Neurology Associates, P.C. | Cullman | Alabama | 35058 | — |
| University of South Alabama | Mobile | Alabama | 36693 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Fullerton Neurology and Headache Center | Fullerton | California | 92835 | — |
| Regina Berkovich MD PhD INC | West Hollywood | California | 90048 | — |
| Colorado Springs Neurological Associates, PC - Neurology | Colorado Springs | Colorado | 80907 | — |
| HCA Research Institute | Englewood | Colorado | 80113 | — |
| Advanced Neurosciences Research, LLC | Fort Collins | Colorado | 80528 | — |
| Associated Neurologists of Southern Connecticut, PC | Fairfield | Connecticut | 06824 | — |
| Yale University | Fairfield | Connecticut | 06824 | — |
| Neurology Associates, P. A. | Maitland | Florida | 32751 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Orlando Health Multiple Sclerosis Comprehensive Care Center - Downtown Orlando | Orlando | Florida | 32806 | — |
| Suncoast Neuroscience and Associates, Inc. | St. Petersburg | Florida | 33713 | — |
| Axiom Clinical Research of Florida | Tampa | Florida | 33609 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Northwest Neurology Ltd | Rolling Meadows | Illinois | 60008 | — |
| Prairie Education & Research | Springfield | Illinois | 62702 | — |
| Fort Wayne Neurological Center | Fort Wayne | Indiana | 46804 | — |
| College Park Family Care Center | Overland Park | Kansas | 66212 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Northern Light Comprehensive Multiple Sclerosis Care Center | Bangor | Maine | 04401 | — |
| Neurological Clinical Research Institute | Boston | Massachusetts | 02114 | — |
| Neuro Institute of New England P.C. | Foxborough | Massachusetts | 02035 | — |
| The Elliot Lewis Center for Multiple Sclerosis Care | Wellesley | Massachusetts | 02481 | — |
| UMASS - Neurology | Worcester | Massachusetts | 01655 | — |
| Wayne State University (WSU) - Multiple Sclerosis Treatment and Clinical Research Center (MS Center) - Department of Neurology | Detroit | Michigan | 48201 | — |
| Detroit Clinical Research Center, PC | Farmington Hills | Michigan | 48334 | — |
| Memorial Healthcare | Owosso | Michigan | 48867 | — |
| Minneapolis Clinic of Neurology - Neurology | Golden Valley | Minnesota | 55422 | — |
| Neurology Center of Las Vegas | Las Vegas | Nevada | 89128 | — |
| DENT Neurologic Institute | Amherst | New York | 14226 | — |
| NYU Langone Brooklyn - Brooklyn | Brooklyn | New York | 11220 | — |
| The Trustee of Columbia University in the City of New York | New York | New York | 10032 | — |
| The Charlotte-Mecklenburg Hospital Authority - Carolinas Healthcare System | Charlotte | North Carolina | 28203 | — |
| Guilford Neurologic Associates | Greensboro | North Carolina | 27405 | — |
| Raleigh Neurology Associates | Raleigh | North Carolina | 27607-6010 | — |
| Insight Neuroscience LLC | Bellevue | Ohio | 44811 | — |
| Riverhills Neuroscience | Cincinnati | Ohio | 45212 | — |
| The Boster Center for Multiple Scelosis | Columbus | Ohio | 43235 | — |
| Dayton Center for Neurological Disorders | Dayton | Ohio | 45459 | — |
| University of Toledo - PARENT | Toledo | Ohio | 43614-2598 | — |
| Providence Neurological Specialties | Portland | Oregon | 97225 | — |
| Wills Eye Institute - Ocular Oncology Service - Wills Eye Institute | Philadelphia | Pennsylvania | 19107 | — |
| Premier Neurology Research, P.C. | Greer | South Carolina | 29650 | — |
| Neurology, PC | Knoxville | Tennessee | 37922 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Northwest Houston Neurology | Cypress | Texas | 77429 | — |
| Baylor College of Medicine IRB | Houston | Texas | 77030 | — |
| DHR Health Neurology Institute Neuroimmunology and Multiple Sclerosis | McAllen | Texas | 78503 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Neurology Center of San Antonio | San Antonio | Texas | 78258 | — |
| Integrated Neurology Services - Dr. Simon Fishman's Office | Alexandria | Virginia | 22310 | — |
| Blacksburg Neurology, PC | Christiansburg | Virginia | 24073 | — |
| Meridian Clinical Research (Neurology) | Norfolk | Virginia | 23502 | — |
| Neurological Associates | Richmond | Virginia | 23226 | — |
| VCU Medical Center - Pediatric Neurology | Richmond | Virginia | 23298-0211 | — |
| Massey Cancer Center - VCU Medical Center | Richmond | Virginia | 23298 | — |
| Multiple Sclerosis Center of Greater Washington | Vienna | Virginia | 22182 | — |
| Sentara Ambulatory Care Center | Virginia Beach | Virginia | 23456 | — |
| MS Center of Evergreen | Kirkland | Washington | 98034 | — |
| MultiCare Health System Institute for Research and Innovation - MultiCare Health System Institute for Research and | Spokane | Washington | 99202 | — |
| MultiCare Health System Institute for Research and Innovation - MultiCare Health System Institute for Research | Tacoma | Washington | 98405 | — |
| Ascension St. Francis Center for Neurological Disorders, S.C. | Milwaukee | Wisconsin | 53215 | — |
| The Medical College of Wisconsin - Endocrinology | Milwaukee | Wisconsin | 53226 | — |
| Neuroscience Group of Northeast Wisconsin - DUPLICATE | Neenah | Wisconsin | 54956 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03933202, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 2, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03933202 live on ClinicalTrials.gov.