DOSE Trial of Opioid Sparing Effect
Public ClinicalTrials.gov record NCT03938857. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
DEXMEDETOMIDINE OPIOID SPARING EFFECT IN MECHANICALLY VENTILATED CHILDREN: Phase 1b, Multicenter, Double Blind Randomized Controlled Dose Escalating Trial of Fentanyl vs. Fentanyl + Dexmedetomidine as the Initial Regimen for Maintenance of Sedation in Mechanically-ventilated, Critically Ill Children
Study identification
- NCT ID
- NCT03938857
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Duke University
- Other
- Enrollment
- 30 participants
Conditions and interventions
Interventions
- Fentanyl Drug
- Dexmedetomidine Drug
Drug
Eligibility (public fields only)
- Age range
- Up to 18 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 17, 2019
- Primary completion
- Oct 20, 2020
- Completion
- Nov 5, 2020
- Last update posted
- Nov 4, 2021
2019 – 2020
United States locations
- U.S. sites
- 19
- U.S. states
- 16
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| University of Florida, Shands Children's Hospital | Gainesville | Florida | 32608 | — |
| Indiana University Health, Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| Our Lady of the Lake Children's Hospital | Baton Rouge | Louisiana | 70808 | — |
| UMass Memorial Medical Center, Children's Center | Worcester | Massachusetts | 01655 | — |
| University of Minnesota Masonic Children's Hospital | Minneapolis | Minnesota | 55454 | — |
| Saint Louis University, Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | — |
| University of New Mexico Children's Hospital | Albuquerque | New Mexico | 87131 | — |
| University of Buffalo, Oishei Children's Hospital | Buffalo | New York | 14203 | — |
| University of Rochester Medical Center, Golisano Children's Hospital | Rochester | New York | 14642 | — |
| Duke University Medical Center | Durham | North Carolina | 27705 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| MetroHealth System, Case CTSA | Cleveland | Ohio | 44109 | — |
| Oregon Health and Science University, Doernbecher Children's Hospital | Portland | Oregon | 97239 | — |
| Drexel University, St. Christopher's Hospital for Children | Philadelphia | Pennsylvania | 19134 | — |
| Medical University of South Carolina Children's Hospital | Charleston | South Carolina | 29425 | — |
| University of Texas - Health Science Center San Antonio | San Antonio | Texas | 78229 | — |
| Primary Children's Medical Center- University of Utah | Salt Lake City | Utah | 84113 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03938857, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 4, 2021 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03938857 live on ClinicalTrials.gov.