Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced, Unresectable Pancreatic Cancer
Public ClinicalTrials.gov record NCT03941093. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study of Pamrevlumab or Placebo in Combination With Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX as Neoadjuvant Treatment in Patients With Locally Advanced, Unresectable Pancreatic Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, randomized, double-blind trial to evaluate the efficacy and safety of neoadjuvant treatment with pamrevlumab or placebo in combination with either gemcitabine plus nab-paclitaxel (G/NP) or FOLFIRINOX in the treatment of participants with locally advanced, unresectable pancreatic cancer.
Study identification
- NCT ID
- NCT03941093
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 284 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 10, 2019 (Actual)
- Primary completion
- Jun 11, 2024 (Actual)
- Completion
- Jun 11, 2024 (Actual)
- Last update posted
- Nov 5, 2024
2019 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 20
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital and Medical Cancer Center | Phoenix | Arizona | 85004 | — |
| UC San Diego Moores Cancer Center | La Jolla | California | 92037 | — |
| UCLA | Los Angeles | California | 90095 | — |
| UC Davis Comprehensive Cancer Center | Sacramento | California | 95817 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Elmhurst Memorial Hospital - Nancy W. Knowles Cancer Center | Elmhurst | Illinois | 60126 | — |
| Edward Cancer Center | Naperville | Illinois | 60540 | — |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Indianapolis | Indiana | 48202 | — |
| University of Kansas Hospital | Westwood | Kansas | 66205 | — |
| Norton Cancer Institute, Audubon Hospital Campus | Louisville | Kentucky | 40217 | — |
| Maine Health Cancer Care | South Portland | Maine | 04106 | — |
| University of Massachusetts | Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Saint Luke's Hospital | Kansas City | Missouri | 64111 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68105 | — |
| New Mexico Cancer Care Alliance | Albuquerque | New Mexico | 87131 | — |
| NYU Langone Health | New York | New York | 11735 | — |
| Stony Brook University | Stony Brook | New York | 11794 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| Ohio State University | Columbus | Ohio | 43210 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Reading Hospital McGlinn Cancer Institute | West Reading | Pennsylvania | 19611 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Baylor Scott & White Medical Center | Temple | Texas | 76508 | — |
| Renovatio Clinic | The Woodlands | Texas | 77380 | — |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 58 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03941093, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 5, 2024 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03941093 live on ClinicalTrials.gov.