Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury (AKI) Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery
Public ClinicalTrials.gov record NCT03941483. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Proof of Concept, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Efficacy of ASP1128 (MA-0217) in Subjects at Risk for Acute Kidney Injury Following Coronary Artery Bypass Graft (CABG) and/or Valve Surgery
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to evaluate the efficacy of postsurgery treatment with ASP1128 in subjects at risk for AKI following CABG and/or valve surgery. This study also investigated the safety and tolerability of postsurgery treatment with ASP1128, and pharmacokinetic characteristics of ASP1128 in subjects at risk for AKI following CABG and/or valve surgery.
Study identification
- NCT ID
- NCT03941483
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 351 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 35 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 1, 2019 (Actual)
- Primary completion
- Jul 26, 2021 (Actual)
- Completion
- Oct 20, 2021 (Actual)
- Last update posted
- Dec 4, 2024
2019 – 2021
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research, LLC | Huntsville | Alabama | 35801 | — |
| Sarver Heart Center | Tucson | Arizona | 85724 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| Health Park Medical Center | Fort Myers | Florida | 33908 | — |
| Shands Hospital | Gainesville | Florida | 32610 | — |
| Florida Hospital Pepin Heart Institute | Tampa | Florida | 33613 | — |
| Southern Illinois University | Springfield | Illinois | 62794 | — |
| Luthern Medical Group | Fort Wayne | Indiana | 46804 | — |
| IU Health - Methodist | Indianapolis | Indiana | 46202 | — |
| St. Vincent Heart Center | Indianapolis | Indiana | 46290 | — |
| Indiana University Health Ball Memorial Hospital | Muncie | Indiana | 47303 | — |
| MercyOne Iowa Heart Center | Des Moines | Iowa | 50314 | — |
| Delmarva Heart, LLC | Salisbury | Maryland | 21804 | — |
| Ascension Genesys Hospital | Grand Blanc | Michigan | 48439 | — |
| Mid Michigan Medical Center | Midland | Michigan | 48670 | — |
| Minneapolis Heart Institute | Minneapolis | Minnesota | 55407 | — |
| Baptist Medical Center | Jackson | Mississippi | 39202 | — |
| St. Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Lourdes Cardiology Services | Voorhees Township | New Jersey | 08035 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Moses H. Cone Memorial Hospital | Greensboro | North Carolina | 27401 | — |
| Fairview Hospital - Cleveland Clinic | Cleveland | Ohio | 44111 | — |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| Baylor Scott & White Heart Hospital | Plano | Texas | 75093 | — |
| University of Texas Health Science Center | San Antonio | Texas | 78229 | — |
| WVU Heart and Vascular Institute | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03941483, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 4, 2024 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03941483 live on ClinicalTrials.gov.