A Study of TAK-018 in Preventing the Recurrence of Crohn's Disease After Surgery
Public ClinicalTrials.gov record NCT03943446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2a Study to Evaluate the Safety, Tolerability, and Early Proof of Concept of TAK-018 for the Prevention of Postoperative Crohn's Disease Recurrence
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main aim is to see if TAK-018 reduces the recurrence of intestinal inflammation after abdominal resection surgery in adults with Crohn's disease. Participants will take either TAK-018 or placebo tablets by mouth, 2 times each day for up to 26 weeks after surgery. The placebo looks like TAK-018 but will not have any medicine in it. Participants will have 6 study visits while receiving treatment. Visits 1 and 6 will be conducted at the study clinic. The others can be in the clinic or at the participant's home. Follow-up will occur 4 weeks after final treatment.
Study identification
- NCT ID
- NCT03943446
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 34 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 4, 2020 (Actual)
- Primary completion
- Aug 25, 2022 (Actual)
- Completion
- Aug 25, 2022 (Actual)
- Last update posted
- Sep 7, 2023
2020 – 2022
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Hoag Memorial Hospital Presbyterian | Los Angeles | California | 92618 | — |
| University of Colorado Hospital Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | — |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | — |
| University of Miami Leonard M. Miller School of Medicine | Miami | Florida | 33136 | — |
| University of South Florida/USF Health | Tampa | Florida | 33612 | — |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40536 | — |
| Johns Hopkins University | Baltimore | Maryland | 21205 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Dartmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| NYU Langone Inflammatory Bowel Disease Center | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Columbia University Irving Medical Center | New York | New York | 10032 | — |
| University of North Carolina School of Medicine | Chapel Hill | North Carolina | 27599-7032 | — |
| Atrium Health | Charlotte | North Carolina | 28204 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213-2536 | — |
| Vanderbilt Inflammatory Bowel Disease Clinic | Nashville | Tennessee | 37212-1375 | — |
| Houston Methodist Hospital | Houston | Texas | 77030-2740 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03943446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 7, 2023 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03943446 live on ClinicalTrials.gov.