Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders

ClinicalTrials.gov ID: NCT03943537

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Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This clinical trial is a single center, single dose study of the acute effects of intranasal insulin on energy metabolism and cognitive function in patients with schizophrenia, schizoaffective and bipolar disorders, compared and healthy controls.

Study identification

NCT ID: NCT03943537
Recruitment status: Completed
Study type: Interventional
Phase: Phase 2
Lead sponsor: Mclean Hospital; Other
Enrollment: 87 participants

Conditions and interventions

Conditions

Interventions

Intranasal Insulin Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 40 Years
Sex: All
Healthy volunteers: Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 1, 2019 (Actual)
Primary completion: Feb 23, 2024 (Actual)
Completion: Feb 23, 2024 (Actual)
Last update posted: Sep 3, 2026

2019 – 2024

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
McLean Hospital	Belmont	Massachusetts	02478	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT03943537, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 3, 2026 · Synced Nov 14, 2026