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Terminated Phase 1 Interventional Results available

A Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)

ClinicalTrials.gov ID: NCT03948763

Public ClinicalTrials.gov record NCT03948763. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 14, 2026, 8:34 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, Open-Label, Multicenter Study to Assess the Safety and Tolerability of mRNA-5671/V941 as a Monotherapy and in Combination With Pembrolizumab in Participants With KRAS Mutant Advanced or Metastatic Non-Small Cell Lung Cancer, Colorectal Cancer or Pancreatic Adenocarcinoma

Study identification

NCT ID
NCT03948763
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
70 participants

Conditions and interventions

Interventions

  • Pembrolizumab Biological
  • V941 Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 25, 2019
Primary completion
Aug 24, 2022
Completion
Aug 24, 2022
Last update posted
Jan 27, 2025

2019 – 2022

United States locations

U.S. sites
10
U.S. states
8
U.S. cities
10
Facility City State ZIP Site status
Banner MD Anderson Cancer Center ( Site 1008) Gilbert Arizona 85234
City of Hope ( Site 1002) Duarte California 91010
University of California at San Francisco ( Site 1006) San Francisco California 30322
Smilow Cancer Hospital at Yale New Haven ( Site 1005) New Haven Connecticut 06510
Dana-Farber Cancer Institute (Boston) ( Site 1007) Boston Massachusetts 02215
Comprehensive Cancer Centers of Nevada ( Site 1012) Las Vegas Nevada 89169
Tennessee Oncology Nashville Drug Development Unit ( Site 7000) Nashville Tennessee 37203
START San Antonio ( Site 1004) San Antonio Texas 78229
Baylor Scott & White Medical Center - Temple ( Site 1009) Temple Texas 76508
Northwest Medical Specialties, PLLC ( Site 1001) Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03948763, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 27, 2025 · Synced May 14, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03948763 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →