ClinicalTrials.gov record
An Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis
ClinicalTrials.gov ID: NCT03950232
Public ClinicalTrials.gov record NCT03950232. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension Study of Etrasimod in Subjects With Moderately to Severely Active Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this open-label extension (OLE) study is to evaluate the safety and efficacy of etrasimod in participants with moderately to severely active ulcerative colitis (UC) who previously received double-blind treatment (either etrasimod 2 mg per day or placebo) during participation in one of the qualified Phase 3 or Phase 2 double-blind, placebo-controlled parent studies including but not limited to: (APD334-301 \[NCT03945188\] or APD334-302 \[NCT03996369\] or APD334-210 \[NCT04607837\]).
Study identification
- NCT ID
- NCT03950232
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 896 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 16 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 5, 2019 (Actual)
- Primary completion
- Jun 19, 2029 (Estimated)
- Completion
- Jun 19, 2029 (Estimated)
- Last update posted
- Jul 9, 2026
2019 – 2029
United States locations
- U.S. sites
- 132
- U.S. states
- 18
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Center for Digestive Health (Colonoscopy Location) | Dothan | Alabama | 36301 | — |
| Digestive Health Specialists (IP Address) | Dothan | Alabama | 36301 | — |
| Flowers Hospital (PFT Location) | Dothan | Alabama | 36301 | — |
| Pulmonary Associates (Secondary PFT Location) | Dothan | Alabama | 36301 | — |
| Gut P.C., dba Digestive Health Specialists of the Southeast (IP Address) | Dothan | Alabama | 36305 | — |
| Inland Pulmonary Specialists [PFT Only] | Lake Elsinore | California | 92532 | — |
| A V Pediatrics,Allergy and Family Medicine | Lancaster | California | 93534 | — |
| Advanced Endoscopy and Pain Center(Colonoscopy) | Lancaster | California | 93534 | — |
| Antelope Valley Eye Care(Ophthalmologist) | Lancaster | California | 93534 | — |
| Jatinder S.Pruthi,MD FACG CPI | Lancaster | California | 93534 | — |
| Om Research LLC | Lancaster | California | 93534 | — |
| Renaissance Imaging Center(Chest X-Ray only) | Lancaster | California | 93534 | — |
| United Surgery Center Murrieta [Endoscopy Only] | Murrieta | California | 92562 | — |
| United Medical Doctors | Murrieta | California | 92563 | — |
| Advanced Imaging (Chest X-Ray) | Palmdale | California | 93551 | — |
| California Eye Professionals [OCT Only] | Temecula | California | 92591 | — |
| United Surgery Center Temecula [Endoscopy Only] | Temecula | California | 92592 | — |
| Front Range Endoscopy Center | Colorado Springs | Colorado | 80903 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80920 | — |
| Bay Area Chest Physicians, P.A.,-(Pulmonary Function Test) | Clearwater | Florida | 33756 | — |
| West Coast Endoscopy Center (Endoscopy Procedures) | Clearwater | Florida | 33756 | — |
| Northwood Vision- Optical Coherence Tomography (OCT) | Clearwater | Florida | 33761 | — |
| Northwood Vision-Optical Coherence Tomography-(OCT) | Clearwater | Florida | 33761 | — |
| Safety Harbor Surgery (Endoscopy Facility) | Clearwater | Florida | 33761 | — |
| Gastro Florida (Regulatory & Administrative Duties) | Clearwater | Florida | 33762 | — |
| Gastro Florida-(Regulatory & Administrative Duties) | Clearwater | Florida | 33762 | — |
| West Coast Endoscopy Center (Endoscopy Procedures) | Clearwater | Florida | 33765 | — |
| Dr Lee Shettle | Largo | Florida | 33771 | — |
| Florida Center for Gastroenterology | Largo | Florida | 33771 | — |
| Tampa Bay Regional Surgery Center | Largo | Florida | 33771 | — |
| NSB Research | New Smyrna Beach | Florida | 32168 | — |
| Tampa Bay Endoscopy Center (ENDO Only) | Tampa | Florida | 33603 | — |
| Tampa Bay Endoscopy Center | Tampa | Florida | 33603 | — |
| Lab - Processing / Storage | Tampa | Florida | 33606 | — |
| USF Health South Tampa Center for Advanced Healthcare | Tampa | Florida | 33606 | — |
| Pulmonary and Sleep of Tampa Bay (PFT Only) | Tampa | Florida | 33607 | — |
| GCP Clinical Research,LLC | Tampa | Florida | 33609 | — |
| LoCicero Medical Group (PFT Procedure Only) | Tampa | Florida | 33609 | — |
| Lyracore Health Alliance (PFT Procedure only) | Tampa | Florida | 33609 | — |
| Newsome Eye Specialist (OCT Procedures Only) | Tampa | Florida | 33609 | — |
| USF Health Morsani Center For Advanced Healthcare | Tampa | Florida | 33612 | — |
| Guardian Angel Research Center, INC | Tampa | Florida | 33614 | — |
| Perez Eye Center (OCT only) | Tampa | Florida | 33614 | — |
| Florida Medical Clinic, LLC (Endoscopy) | Zephyrhills | Florida | 33542 | — |
| Florida Medical Clinic, LLC (OCT) | Zephyrhills | Florida | 33542 | — |
| Florida Medical Clinic, LLC (PFT) | Zephyrhills | Florida | 33542 | — |
| Florida Medical Clinic, LLC | Zephyrhills | Florida | 33542 | — |
| Emory Pulmonary Function Tedt Lab | Atlanta | Georgia | 30322 | — |
| Emory Pulmonary Group (PFT only) | Atlanta | Georgia | 30324 | — |
| Atlanta Gastroenterology Associates (Endoscopy Location) | Atlanta | Georgia | 30342 | — |
| Atlanta Gastroenterology Associates (endoscopy only) | Atlanta | Georgia | 30342 | — |
| Atlanta Gastroenterology Associates (Screening and Recruitment) | Atlanta | Georgia | 30342 | — |
| Atlanta Gastroenterology Associates(IP only) | Atlanta | Georgia | 30342 | — |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | — |
| Emory Saint Joseph Pulmonary Function Test Lab | Atlanta | Georgia | 30342 | — |
| Thomas Eye Group (OCT only) | Sandy Springs | Georgia | 30328 | — |
| Illinois Gastroenterology Group dba GI Alliance (Patients seen; IP Delivered) | Gurnee | Illinois | 60031 | — |
| Medical Eye Services LTD (Ophthalmoscopy with OCT) | Gurnee | Illinois | 60031 | — |
| North Shore Endoscopy Center (Endoscopy) | Lake Bluff | Illinois | 60044 | — |
| Libertyville Imaging Center (Diagnostic Imaging) | Libertyville | Illinois | 60048 | — |
| Eye Medical Center (OCT location) | Baton Rouge | Louisiana | 70808 | — |
| Baton Rouge LA Endoscopy | Baton Rouge | Louisiana | 70809 | — |
| Chevy Chase Pulmonary Associate (PFT Only) | Chevy Chase | Maryland | 20815 | — |
| Friendship Heights Endoscopy Center (Endoscopy Facility Only) | Chevy Chase | Maryland | 20815 | — |
| Retina Group Of Washington (OCT Only) | Chevy Chase | Maryland | 20815 | — |
| Barnes-Jewish West County Hospital (Additional Endoscopy Location) | Creve Coeur | Missouri | 63141 | — |
| Washington University School of Medicine | St Louis | Missouri | 63108 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Durango Surgical Center | Las Vegas | Nevada | 89113 | — |
| Abrams Eye Institute (OCT) | Las Vegas | Nevada | 89148 | — |
| Lung Center of Nevada | Las Vegas | Nevada | 89148 | — |
| Duke Medical Plaza North Duke Street | Durham | North Carolina | 27704 | — |
| Duke Eye Center (OCT only) | Durham | North Carolina | 27705 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Investigational Drug Services (Pharmacy) | Durham | North Carolina | 27710 | — |
| Brier Creek Medical Pavilion | Raleigh | North Carolina | 27617 | — |
| Geauga Sleep Center (PFT Only) | Chardon | Ohio | 44024 | — |
| UC Health Hoxworth (OCT only) | Cincinnati | Ohio | 45219 | — |
| UC Health Physicians Office | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati Medical Center (PFT and Endoscopy location) | Cincinnati | Ohio | 45219 | — |
| UC Health (Pulmonary Function Testing) | Cincinnati | Ohio | 45229 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| Ophthalmic Physicians Incorporated (OCT Only) | Mentor | Ohio | 44060 | — |
| The Endoscopy Center of Lake County | Mentor | Ohio | 44060 | — |
| Vitreo Retinal Consultants (OCT only) | Mentor | Ohio | 44060 | — |
| Lake Pulmonary Associates (PFT only) | Willoughby Hills | Ohio | 44094 | — |
| Retina Specialist of Ohio (OCT only) | Willoughby Hills | Ohio | 44094 | — |
| Digestive Disease Specialists, Inc. Endoscopy Lab | Oklahoma City | Oklahoma | 73112 | — |
| Pulmonary Physicians of Oklahoma | Oklahoma City | Oklahoma | 73112 | — |
| Retina Center of Oklahoma | Oklahoma City | Oklahoma | 73112 | — |
| Susquehanna Research Group | Camp Hill | Pennsylvania | 17011 | — |
| West Shore Endoscopy Center | Camp Hill | Pennsylvania | 17011 | — |
| Farrell Ophthalmology (OCT only) | Harrisburg | Pennsylvania | 17110 | — |
| Susquehanna Research Group, LLC | Harrisburg | Pennsylvania | 17110 | — |
| Harrisburg Eye Associates (OCT only) | Harrisburg | Pennsylvania | 17111 | — |
| Medical Arts Allergy,PC (PFT Only) | Harrisburg | Pennsylvania | 17111 | — |
| Pulmonary and Critical Care Medicine Associates (PFT only) | Lemoyne | Pennsylvania | 17043 | — |
| Cross Timbers Surgery Center(Proctosigmoidoscopy) | Arlington | Texas | 76012 | — |
| Envision Imaging(Chest X-Ray) | Arlington | Texas | 76012 | — |
| Texas Clinical Research Institute | Arlington | Texas | 76012 | — |
| Texas Pulmonary and Critical Care Associates(Pulmonary Function Test) | Arlington | Texas | 76012 | — |
| Texas Retina Associates(Ophthalmoscopy) | Arlington | Texas | 76012 | — |
| Inquest Clinical Research | Baytown | Texas | 77521 | — |
| Texas Retina Associates (OCT Location) | Grapevine | Texas | 76051 | — |
| Plaza Medical Center | Houston | Texas | 77004 | — |
| East Houston Physicians Group | Houston | Texas | 77029 | — |
| Baylor College of Medicine- Baylor Medical Center | Houston | Texas | 77030 | — |
| Cross Eye Center (Optical Coherence Tomography) | Houston | Texas | 77401 | — |
| Lonestar Endoscopy(Endoscopy Location) | Keller | Texas | 76248 | — |
| Christus Santa Rosa Physicians Ambulatory Surgery Center New Braunfels (Endoscopy) | New Braunfels | Texas | 78130 | — |
| Tyrus Schroeder (PFT) | New Braunfels | Texas | 78130 | — |
| Central Texas Eye Center (OCT) | San Marcos | Texas | 78666 | — |
| Christus Santa Rosa Physicians Ambulatory Surgery Center San Marcos (Endoscopy) | San Marcos | Texas | 78666 | — |
| Envision Imaging (Chest X-ray location) | Southlake | Texas | 76092 | — |
| Lonestar Endoscopy (Endoscopy Location) | Southlake | Texas | 76092 | — |
| Christus Trinity Mother Frances Endosopy Center ( endoscopies only) | Tyler | Texas | 75701 | — |
| Heaton Eye Associates (OCT only) | Tyler | Texas | 75701 | — |
| Touchstone Imaging Tyler (chest x-rays only) | Tyler | Texas | 75701 | — |
| Tyler Internal Medicine (PFT's only) | Tyler | Texas | 75701 | — |
| UT Health East Texas Physicians (pulmonary functions only) | Tyler | Texas | 75701 | — |
| Gastro Health & Nutrition | Victoria | Texas | 77904 | — |
| Harman Eye Center (OCT only) | Forest | Virginia | 24551 | — |
| Lynchburg Pulmonary Associates, Inc. (PFT only) | Lynchburg | Virginia | 24501 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | — |
| Swedish Endoscopy Center - Issaquah | Issaquah | Washington | 98029 | — |
| Pacific Northwest Retina | Seattle | Washington | 98104 | — |
| Richard Bensinger, MD | Seattle | Washington | 98104 | — |
| Swedish Gastroenterology | Seattle | Washington | 98104 | — |
| Swedish Medical Center First Hill Endoscopy Center | Seattle | Washington | 98122 | — |
| Swedish Medical Center First Hill | Seattle | Washington | 98122 | — |
| Froedtert Memorial Lutheran Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 338 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03950232, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 9, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03950232 live on ClinicalTrials.gov.