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Completed Phase 1 Interventional Results available

Open-label, Clinical Study to Evaluate the Safety and Tolerability of TreT in Subjects With PAH Currently Using Tyvaso

ClinicalTrials.gov ID: NCT03950739

Public ClinicalTrials.gov record NCT03950739. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 5:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Clinical Study to Evaluate the Safety and Tolerability of Treprostinil Inhalation Powder (TreT) in Subjects With Pulmonary Arterial Hypertension Currently Using Tyvaso

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This was a Phase 1b safety and tolerability single-sequence study in which PAH subjects on a stable regimen of Tyvaso switched to a corresponding dose of TreT.

Study identification

NCT ID
NCT03950739
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
United Therapeutics
Industry
Enrollment
51 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 16, 2019
Primary completion
Aug 21, 2023
Completion
Aug 21, 2023
Last update posted
Oct 31, 2024

2019 – 2023

United States locations

U.S. sites
16
U.S. states
11
U.S. cities
15
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35233
Department of Veterans Affairs Greater Los Angeles Healthcare System Los Angeles California 90073
Ascension / St. Vincent's Lung Institute Jacksonville Florida 32204
Mayo Clinic Florida Jacksonville Florida 32224
University of South Florida Center for Advanced Lung Disease Tampa Florida 33606
Cleveland Clinic Florida Weston Florida 33331
Emory University Hospital Atlanta Georgia 30322
The University of Kansas Medical Center Kansas City Kansas 66160
University of Louisville Clinical Trials Unit Louisville Kentucky 40202
Ochsner Medical Center New Orleans Louisiana 70121
University of Maryland Medical Center Division of Cardiology Baltimore Maryland 21201
Penn Medicine University City Philadelphia Pennsylvania 19104
UT Southwestern Medical Center Dallas Texas 75390
Houston Methodist Hospital Houston Texas 77030
Sentara Norfolk General Hospital Norfolk Virginia 23507
Pulmonary Associates of Richmond, Inc. Richmond Virginia 23230

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03950739, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 31, 2024 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03950739 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →