Lot-to-Lot Consistency of V114 in Healthy Adults (V114-020)
Public ClinicalTrials.gov record NCT03950856. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator-controlled, Lot-to-Lot Consistency Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Healthy Adults 50 Years of Age or Older (PNEU-TRUE)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objectives are to evaluate the safety and tolerability of V114 and to compare the serotype-specific opsonophagocytic activity (OPA) geometric mean titers (GMTs) across 3 different lots of V114. The primary hypothesis is that all 3 lots of V114 are equivalent as measured by the serotype-specific OPA GMTs for 15 serotypes in V114 at 30 days postvaccination.
Study identification
- NCT ID
- NCT03950856
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 2,340 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 12, 2019 (Actual)
- Primary completion
- Apr 3, 2020 (Actual)
- Completion
- Apr 3, 2020 (Actual)
- Last update posted
- Apr 12, 2021
2019 – 2020
United States locations
- U.S. sites
- 30
- U.S. states
- 15
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Synexus Clinical Research US, Inc. ( Site 1031) | Chandler | Arizona | 85224 | — |
| Synexus ( Site 1043) | Mesa | Arizona | 85206 | — |
| Southland Clinical Research Center ( Site 1027) | Fountain Valley | California | 92708 | — |
| Valley Clinical Trials Inc. ( Site 1003) | Northridge | California | 91325 | — |
| Center for Clinical Trials, LLC ( Site 1019) | Paramount | California | 90723 | — |
| California Research Foundation ( Site 1006) | San Diego | California | 92123 | — |
| Artemis Institute for Clinical Research ( Site 1041) | San Marcos | California | 92078 | — |
| Alta California Medical Group ( Site 1020) | Simi Valley | California | 93065 | — |
| Alliance for Multispecialty Research, LLC ( Site 1029) | Coral Gables | Florida | 33134 | — |
| Accel Research Sites-DeLand Clinical Research Unit ( Site 1026) | DeLand | Florida | 32720 | — |
| Jacksonville Center for Clinical Research ( Site 1014) | Jacksonville | Florida | 32216 | — |
| L&C Professional Medical Research Institute ( Site 1012) | Miami | Florida | 33144 | — |
| Alpha Science Research ( Site 1015) | Miami | Florida | 33186 | — |
| QPS Miami Research Associates ( Site 1035) | South Miami | Florida | 33143 | — |
| Benchmark Research ( Site 1040) | Metairie | Louisiana | 70006 | — |
| Centennial Medical Group ( Site 1010) | Elkridge | Maryland | 21075 | — |
| Community Clinical Research Network (Marlboro, MA) ( Site 1025) | Marlborough | Massachusetts | 01752 | — |
| Wake Research Clinical Research Center of Nevada, LLC ( Site 1044) | Las Vegas | Nevada | 89104 | — |
| Southwest CARE Center ( Site 1011) | Santa Fe | New Mexico | 87505 | — |
| Corning Center For Clinical Research ( Site 1033) | Corning | New York | 14830 | — |
| Regional Clinical Research, Inc. ( Site 1024) | Endwell | New York | 13760 | — |
| Rochester Clinical Research, Inc. ( Site 1039) | Rochester | New York | 14609 | — |
| PMG Research of Winston Salem ( Site 1037) | Winston-Salem | North Carolina | 27103 | — |
| Unity Clinical Research ( Site 1036) | Lindsay | Oklahoma | 73052 | — |
| Coastal Carolina Research Center ( Site 1034) | Mt. Pleasant | South Carolina | 29464 | — |
| Wellness Clinical Research Associates ( Site 1038) | Allen | Texas | 75013 | — |
| Diagnostics Research Group ( Site 1042) | San Antonio | Texas | 78229 | — |
| Synexus ( Site 1000) | Murray | Utah | 84123 | — |
| Advanced Clinical Research ( Site 1028) | West Jordan | Utah | 84088 | — |
| Allegiance Research Specialists ( Site 1013) | Wauwatosa | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 25 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03950856, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2021 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03950856 live on ClinicalTrials.gov.