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Completed Phase 1Phase 2 Interventional

A Study of a Personalized Cancer Vaccine Targeting Shared Neoantigens

ClinicalTrials.gov ID: NCT03953235

Public ClinicalTrials.gov record NCT03953235. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 14, 2026, 7:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Study of GRT-C903/GRT-R904, a Vaccine Targeting Shared Neoantigens, in Combination With Immune Checkpoint Blockade for Patients With Advanced Solid Tumors

Study identification

NCT ID
NCT03953235
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Gritstone bio, Inc.
Industry
Enrollment
39 participants

Conditions and interventions

Interventions

  • GRT-C903 Biological
  • GRT-R904 Biological
  • ipilimumab Biological
  • nivolumab Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 17, 2019
Primary completion
Mar 9, 2023
Completion
Mar 9, 2023
Last update posted
Sep 12, 2023

2019 – 2023

United States locations

U.S. sites
12
U.S. states
11
U.S. cities
11
Facility City State ZIP Site status
Mayo Clinic Arizona Phoenix Arizona 85054
UCLA Medical Center Santa Monica California 90404
Mayo Clinic Florida Jacksonville Florida 32224
University of Chicago Medicine, Comprehensive Cancer Center Chicago Illinois 60637
Mayo Clinic Rochester Rochester Minnesota 55905
Columbia University Medical Center, Herbert Irving Comprehensive Cancer Center New York New York 10032
Memorial Sloan Kettering Cancer Center New York New York 10065
The Ohio State University Comprehensive Cancer Center Columbus Ohio 43210
Fox Chase Cancer Center Philadelphia Pennsylvania 19111
Tennessee Oncology Nashville Tennessee 37203
MD Anderson Cancer Center Houston Texas 77030
Virginia Cancer Specialists Fairfax Virginia 22031

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03953235, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 12, 2023 · Synced May 14, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03953235 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →