A Study to Evaluate the Efficacy and Safety of BIIB093 in Participants With Brain Contusion
Public ClinicalTrials.gov record NCT03954041. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Double-Blind, Multidose, Placebo-Controlled, Randomized, Parallel-Group, Phase 2 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 for Patients With Brain Contusion
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective is to determine if BIIB093 reduces brain contusion expansion by Hour 96 when compared to placebo. The secondary objectives are to evaluate the effects of BIIB093 on acute neurologic status, functional outcomes, and treatment requirements, to further differentiate the mechanism of action of BIIB093 on contusion expansion by examining differential effects on hematoma and edema expansion, and to determine if BIIB093 improves survival at Day 90 when compared to placebo.
Study identification
- NCT ID
- NCT03954041
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 92 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 6, 2019 (Actual)
- Primary completion
- Jun 27, 2023 (Actual)
- Completion
- Jun 27, 2023 (Actual)
- Last update posted
- Nov 27, 2024
2019 – 2023
United States locations
- U.S. sites
- 25
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Scottsdale Healthcare Hospitals d/b/a HonorHealth | Scottsdale | Arizona | 85258 | — |
| University of Arizona Medical Center | Tucson | Arizona | 85724 | — |
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| WellStar Medical Group Neurosurgery | Marietta | Georgia | 30060 | — |
| Goodman Campbell Brain and Spine | Carmel | Indiana | 46032 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70119 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Northwell Health | Manhattan | New York | 11030 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27514 | — |
| Vidant Medical Center | Greenville | North Carolina | 27834 | — |
| Wake Forest Baptist Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati College of Medicine | Cincinnati | Ohio | 45219 | — |
| Miami Valley Hospital | Dayton | Ohio | 45409 | — |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Rhode Island Hospital | East Providence | Rhode Island | 02915-2237 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| University of Utah Health | Salt Lake City | Utah | 84132 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298-0599 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03954041, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 27, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03954041 live on ClinicalTrials.gov.