Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal Polyps
Public ClinicalTrials.gov record NCT03960580. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 24-Week Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of Intranasal Administration of 186 and 372 μg of OPN-375 Twice a Day (BID) in Subjects With Chronic Rhinosinusitis Without the Presence of Nasal Polyps
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 24-week randomized, double-blind, placebo-controlled, parallel-group, multicenter study to evaluate the efficacy and safety of intranasal administration of 186 and 372 μg twice daily (BID) of OPN-375 in subjects with chronic Rhinosinusitis (CRS) without nasal polyps
Study identification
- NCT ID
- NCT03960580
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 223 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 5, 2019
- Primary completion
- May 3, 2022
- Completion
- May 3, 2022
- Last update posted
- Dec 20, 2023
2019 – 2022
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Sacramento Ear, Nose & Throat Surgical and Medical Group Inc | Folsom | California | 95630 | — |
| BioSolutions Clinical Research Center | La Mesa | California | 91942-3007 | — |
| Veterans Administration Greater Los Angeles Healthcare System | Los Angeles | California | 90073 | — |
| Sacramento Ear, Nose & Throat Surgical and Medical Group | Roseville | California | 95661 | — |
| Asthma and Allergy Associates | Colorado Springs | Colorado | 80907 | — |
| Sher Allergy Specialists | Largo | Florida | 33778 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| Best Clinical Trials | New Orleans | Louisiana | 70115 | — |
| University of Missouri, Dept of Otorlaryngology | Columbia | Missouri | 65212 | — |
| Mount Sinai Downtown Union Square | New York | New York | 10003 | — |
| Northwell Health at ENT and Allergy Associates | New York | New York | 10016 | — |
| Charlotte Eye Ear Nose and Throat Assoc., PA | Matthews | North Carolina | 28105 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15219 | — |
| ENT & Allergy Partners, LLC | Summerville | South Carolina | 29486 | — |
| Pasha Snoring & Sinus Center | Houston | Texas | 77082 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23507 | — |
| Allergy, Asthma & Sinus Center, SC | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 67 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03960580, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 20, 2023 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03960580 live on ClinicalTrials.gov.