Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment
Public ClinicalTrials.gov record NCT03968159. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment (ACP-103-054/059)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
To evaluate the efficacy and safety of adjunctive pimavanserin compared to placebo in subjects with major depressive disorder who have an inadequate response to antidepressant therapy
Study identification
- NCT ID
- NCT03968159
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 298 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 25, 2019 (Actual)
- Primary completion
- Apr 30, 2020 (Actual)
- Completion
- May 29, 2020 (Actual)
- Last update posted
- Nov 17, 2021
2019 – 2020
United States locations
- U.S. sites
- 41
- U.S. states
- 20
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham (UAB) | Birmingham | Alabama | 35233 | — |
| CNS Network | Garden Grove | California | 92845 | — |
| Behavioral Research Specialists | Glendale | California | 91206 | — |
| Sun Valley Research Center | Imperial | California | 92251 | — |
| Irvine Clinical Research | Irvine | California | 92614 | — |
| Synergy San Diego | Lemon Grove | California | 91945 | — |
| Pacific Research Partners, LLC | Oakland | California | 94607 | — |
| NRC Research Institute | Orange | California | 92868 | — |
| MCB Clinical Research Centers, LLC | Colorado Springs | Colorado | 80910 | — |
| Mountain View Clinical Research, Inc. | Denver | Colorado | 80209 | — |
| CT Clinical Research | Cromwell | Connecticut | 06416 | — |
| Clinical Neuroscience Solutions ( CNS Healthcare)-Jacksonville | Jacksonville | Florida | 32256 | — |
| Meridien Research | Maitland | Florida | 32751 | — |
| Florida Research Center, Inc. | Miami | Florida | 33174 | — |
| CNS Health Care (Orlando) | Orlando | Florida | 32801 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Synexus Clinical Research | Atlanta | Georgia | 30328 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Capstone Clinical Research | Libertyville | Illinois | 60048 | — |
| Collective Medical Research, LLC | Prairie Village | Kansas | 66208 | — |
| Clinical Trials of America (Monroe, LA) | Monroe | Louisiana | 71201 | — |
| Adams Clinical | Watertown | Massachusetts | 02472 | — |
| St. Charles Psychiatric Associates-Midwest Research Group | Saint Charles | Missouri | 63304 | — |
| Integrative Clinical Trials | Brooklyn | New York | 11229 | — |
| Social Psychiatry Research Institute (SPRI) | Brooklyn | New York | 11235 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| The Medical Research Network, LLC | New York | New York | 10128 | — |
| Finger Lake Clinical Research | Rochester | New York | 14618 | — |
| Clinical Trial of America, LLC | Hickory | North Carolina | 28601 | — |
| Charak Clinical Research Center | Garfield Heights | Ohio | 44125 | — |
| Summit Research Network (Oregon) Inc. | Portland | Oregon | 97210 | — |
| University Of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 26464 | — |
| Psychiatric Consultants, PC | Franklin | Tennessee | 37067 | — |
| Clinical Neuroscience Solutions CNS Healthcare | Memphis | Tennessee | 38119 | — |
| Research Strategies of Memphis, LLC | Memphis | Tennessee | 38119 | — |
| Future Search Trials of Dallas | Dallas | Texas | 75231 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Clinical Trials of Texas, Inc. | San Antonio | Texas | 78229 | — |
| Grayline Research Center | Wichita Falls | Texas | 76309 | — |
| IPC Research | Waukesha | Wisconsin | 53188 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03968159, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 17, 2021 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03968159 live on ClinicalTrials.gov.