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Completed Phase 3 Interventional Results available

Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment

ClinicalTrials.gov ID: NCT03968159

Public ClinicalTrials.gov record NCT03968159. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 4:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment (ACP-103-054/059)

Study identification

NCT ID
NCT03968159
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
ACADIA Pharmaceuticals Inc.
Industry
Enrollment
298 participants

Conditions and interventions

Interventions

  • Pimavanserin Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 24, 2019
Primary completion
Apr 29, 2020
Completion
May 28, 2020
Last update posted
Nov 16, 2021

2019 – 2020

United States locations

U.S. sites
41
U.S. states
20
U.S. cities
37
Facility City State ZIP Site status
University of Alabama at Birmingham (UAB) Birmingham Alabama 35233
CNS Network Garden Grove California 92845
Behavioral Research Specialists Glendale California 91206
Sun Valley Research Center Imperial California 92251
Irvine Clinical Research Irvine California 92614
Synergy San Diego Lemon Grove California 91945
Pacific Research Partners, LLC Oakland California 94607
NRC Research Institute Orange California 92868
MCB Clinical Research Centers, LLC Colorado Springs Colorado 80910
Mountain View Clinical Research, Inc. Denver Colorado 80209
CT Clinical Research Cromwell Connecticut 06416
Clinical Neuroscience Solutions ( CNS Healthcare)-Jacksonville Jacksonville Florida 32256
Meridien Research Maitland Florida 32751
Florida Research Center, Inc. Miami Florida 33174
CNS Health Care (Orlando) Orlando Florida 32801
Emory University School of Medicine Atlanta Georgia 30322
Synexus Clinical Research Atlanta Georgia 30328
Great Lakes Clinical Trials Chicago Illinois 60640
Capstone Clinical Research Libertyville Illinois 60048
Collective Medical Research, LLC Prairie Village Kansas 66208
Clinical Trials of America (Monroe, LA) Monroe Louisiana 71201
Adams Clinical Watertown Massachusetts 02472
St. Charles Psychiatric Associates-Midwest Research Group Saint Charles Missouri 63304
Integrative Clinical Trials Brooklyn New York 11229
Social Psychiatry Research Institute (SPRI) Brooklyn New York 11235
Mount Sinai Hospital New York New York 10029
The Medical Research Network, LLC New York New York 10128
Finger Lake Clinical Research Rochester New York 14618
Clinical Trial of America, LLC Hickory North Carolina 28601
Charak Clinical Research Center Garfield Heights Ohio 44125
Summit Research Network (Oregon) Inc. Portland Oregon 97210
University Of Pennsylvania Philadelphia Pennsylvania 19104
Coastal Carolina Research Center Mt. Pleasant South Carolina 26464
Psychiatric Consultants, PC Franklin Tennessee 37067
Clinical Neuroscience Solutions CNS Healthcare Memphis Tennessee 38119
Research Strategies of Memphis, LLC Memphis Tennessee 38119
Future Search Trials of Dallas Dallas Texas 75231
Baylor College of Medicine Houston Texas 77030
Clinical Trials of Texas, Inc. San Antonio Texas 78229
Grayline Research Center Wichita Falls Texas 76309
IPC Research Waukesha Wisconsin 53188

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 44 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03968159, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 16, 2021 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03968159 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →