A Double-blind Study to Assess 2 Doses of an Investigational Product for 16 Weeks in Participants With Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
Public ClinicalTrials.gov record NCT03969719. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2A, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 3-ARM, PARALLEL GROUP STUDY TO EVALUATE SAFETY, TOLERABILITY AND PHARMACODYNAMICS OF PF-06835919 ADMINISTERED DAILY FOR 16 WEEKS IN ADULTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND TYPE 2 DIABETES MELLITUS ON METFORMIN
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a double-blind, placebo-controlled study in adults with non-alcoholic steatohepatitis and Type 2 Diabetes Mellitis on stable dose of metformin monotherapy. Participants will be treated for 16 weeks with placebo or 1 of 2 doses of investigational product to determine the effect on liver fat, HbA1c, safety, tolerability and pharmacodynamics.
Study identification
- NCT ID
- NCT03969719
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 164 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 18, 2019 (Actual)
- Primary completion
- Mar 2, 2021 (Actual)
- Completion
- Mar 30, 2021 (Actual)
- Last update posted
- May 11, 2022
2019 – 2021
United States locations
- U.S. sites
- 86
- U.S. states
- 15
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Horizon Clinical Research Associates, PLLC | Gilbert | Arizona | 85295 | — |
| Clinical Research Consortium an AMR company | Tempe | Arizona | 85207 | — |
| Anaheim Clinical Trials LLC-Clinical Research | Anaheim | California | 92801 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| San Diego Imaging SDI | Chula Vista | California | 91911 | — |
| Sharp Coronado Hospital | Coronado | California | 92118 | — |
| Southern California Research Center | Coronado | California | 92118 | — |
| Holy Trinity Medical Clinic | Harbor City | California | 90710 | — |
| Innovative Clinical Research, Inc. | Harbor City | California | 90710 | — |
| ICM Medical Group | Inglewood | California | 90301 | — |
| eStudySite | La Mesa | California | 91942 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| National Research Institute | Los Angeles | California | 90057 | — |
| Renaissance Imaging Medical Associates | Northridge | California | 91328 | — |
| Huntington Medical Research Institute | Pasadena | California | 91105 | — |
| Inland Empire Clinical Trials, LLC | Rialto | California | 92377 | — |
| Diagnostic Radiological Imaging Sacramento | Sacramento | California | 95825 | — |
| Precision Research Institute | San Diego | California | 92114 | — |
| Sharp and Children's MRI Center, LLC | San Diego | California | 92123-2731 | — |
| Sharp & Children's MRI Center, LLC | San Diego | California | 92123 | — |
| West Coast Radiology | Santa Ana | California | 92705 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Liberty Pacific Advanced Imaging | Tarzana | California | 91356 | — |
| Advanced Gastroenterology | Thousand Oaks | California | 91360 | — |
| University Clinical Investigators, Incorporated | Tustin | California | 92780 | — |
| Independant Imaging | Atlantis | Florida | 33461 | — |
| Twin Lakes Imaging | Daytona Beach | Florida | 32117 | — |
| Life Radiology | Doral | Florida | 33122 | — |
| MD Clinical LLC | Hallandale | Florida | 33009 | — |
| Borland Groover | Jacksonville | Florida | 32256 | — |
| Multi-Specialty Research Associates, Inc. | Lake City | Florida | 32055 | — |
| Health Care Family Rehab and Research Center | Miami | Florida | 33015 | — |
| Clinical Research of Miami | Miami | Florida | 33126 | — |
| Finlay Medical Research | Miami | Florida | 33126 | — |
| Suncoast Research Group, LLC | Miami | Florida | 33135 | — |
| Unique Imaging | Miami | Florida | 33137 | — |
| Y & L Advance Health Care, Inc D/B/A Elite Clinical Research | Miami | Florida | 33144 | — |
| Stand Up MRI of Miami | Miami | Florida | 33145 | — |
| Vital Imaging Center | Miami | Florida | 33173 | — |
| Vital Imaging | Miami | Florida | 33173 | — |
| Unique Imaging | Miami | Florida | 33180 | — |
| International Research Associates | Miami | Florida | 33183 | — |
| Panax Clinical Research | Miami Lakes | Florida | 33014 | — |
| Advanced Gastroenterology Associates, LLC | Palm Harbor | Florida | 34684 | — |
| Rose Radiology | Palm Harbor | Florida | 34685 | — |
| Castillo & Torres MD PA | Palm Springs | Florida | 33406 | — |
| Ctmd Research Inc | Palm Springs | Florida | 33406 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Qps-Mra, Llc | South Miami | Florida | 33143 | — |
| Physicians Research Associates , LLC | Lawrenceville | Georgia | 30046 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Alliance Multispecialty Research, LLC | Wichita | Kansas | 67207 | — |
| AA MRC | Flint | Michigan | 48504 | — |
| Nebraska Medicine | Omaha | Nebraska | 68198 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Excel Clinical Research | Las Vegas | Nevada | 89109 | — |
| Alliance for Multispecialty, LLC | Las Vegas | Nevada | 89119 | — |
| Desert Radiology | Las Vegas | Nevada | 89128 | — |
| Pueblo Imaging | Las Vegas | Nevada | 89128 | — |
| Northwell Imaging of Garden City | Garden City | New York | 11530 | — |
| Northwell Health - Center for Liver Diseases and Transplantation | Manhasset | New York | 11030 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Gastroenterology Associates of the Piedmont, PA | Winston-Salem | North Carolina | 27103 | — |
| PMG Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| ProScan | Cincinnati | Ohio | 45227 | — |
| RAS Health | Marion | Ohio | 43302 | — |
| Dallas Diabetes and Endocrine Research Center | Dallas | Texas | 75230 | — |
| Southwest Diagnostics Imaging Center | Dallas | Texas | 75231 | — |
| PrimeCare Medical Group | Houston | Texas | 77024 | — |
| Endocrine IPS, PLLC | Houston | Texas | 77079 | — |
| The Endocrine Center | Houston | Texas | 77079 | — |
| Texas Center for Drug Development | Houston | Texas | 77081 | — |
| Houston Medical Imaging | Houston | Texas | 77098 | — |
| South Texas Radiology Imaging Centers | Live Oak | Texas | 78233 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| STRIC Northeast Imaging Center | San Antonio | Texas | 78233 | — |
| Northeast Clinical Research of San Antonio, LLC (NECRSA, LLC) | Schertz | Texas | 78154 | — |
| Clinical Research Partners, LLC | Richmond | Virginia | 23236 | — |
| Virginia Endoscopy Group | Richmond | Virginia | 23236 | — |
| VCU Gateway Building Basement | Richmond | Virginia | 23298 | — |
| Salem VA Medical Center | Salem | Virginia | 24153 | — |
| Harborview Medical Center Investigational Drug Services | Seattle | Washington | 98104 | — |
| Harborview Medical Center | Seattle | Washington | 98104 | — |
| University of Washington Medical Center | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03969719, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 11, 2022 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03969719 live on ClinicalTrials.gov.