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Completed Phase 1 Interventional

A Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Participants With Multiple Sclerosis

ClinicalTrials.gov ID: NCT03972306

Public ClinicalTrials.gov record NCT03972306. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 11:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase Ib, Open-Label, Multicenter Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Patients With Multiple Sclerosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the pharmacokinetics, safety and tolerability, and immunogenicity of ocrelizumab administered subcutaneously to participants with multiple sclerosis (MS).

Study identification

NCT ID
NCT03972306
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
134 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 11, 2019
Primary completion
Jun 2, 2025
Completion
Jun 2, 2025
Last update posted
Jul 7, 2025

2019 – 2025

United States locations

U.S. sites
18
U.S. states
13
U.S. cities
18
Facility City State ZIP Site status
University of Colorado Aurora Colorado 80045
Georgetown University Medical Center Washington D.C. District of Columbia 20007
The NeuroMedical Clinic of Central Louisiana Alexandria Louisiana 71301
Ochsner Clinic Foundation New Orleans Louisiana 70121
John Hopkins University School of Medicine Baltimore Maryland 21287
University of Massachusetts Medical School Worcester Massachusetts 01655
Wayne State University Detroit Michigan 48201
Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis Owosso Michigan 48867
Washington Univ School of Med St Louis Missouri 63110
Columbia University Medical Center New York New York 10032
Cleveland Clinic Mellen Center Cleveland Ohio 44195
UC Health Neurology Dayton Ohio 45417
University of Pennsylvania Philadelphia Pennsylvania 19104
University of Pittsburgh Pittsburgh Pennsylvania 15213
Neurology Clinic PC Cordova Tennessee 38018
University of Texas at Houston Houston Texas 77030
Swedish Neuroscience Institute Seattle Washington 98122
MultiCare Health System Institute for Research and Innovation Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03972306, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 7, 2025 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03972306 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →