A Study Assessing the Safety, Tolerability, and Efficacy of Galegenimab (FHTR2163) in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT03972709. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Randomized, Single-Masked, Sham-Controlled Study to Assess Safety, Tolerability, and Efficacy of Intravitreal Injections of FHTR2163 in Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration (GALLEGO)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the safety, tolerability, and efficacy of intravitreal injections of galegenimab (FHTR2163) administered every 4 weeks (Q4W) or every 8 weeks (Q8W) for approximately 76 weeks in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) compared with sham control. After completing the study's last visit (Week 76), eligible participants will have the option to enroll in open-label extension study NCT04607148 (GR42558) and receive open-label galegenimab (FHTR2163) injections.
Study identification
- NCT ID
- NCT03972709
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 372 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 2, 2019
- Primary completion
- Oct 26, 2022
- Completion
- Oct 26, 2022
- Last update posted
- Mar 26, 2024
2019 – 2022
United States locations
- U.S. sites
- 72
- U.S. states
- 27
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85016 | — |
| Retina Associates Southwest PC | Tucson | Arizona | 85704 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835-3424 | — |
| Jules Stein Eye Institute/ UCLA | Los Angeles | California | 90095-7000 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| Retinal Consultants Med Group | Sacramento | California | 95825 | — |
| W Coast Retina Med Group Inc | San Francisco | California | 94107 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| California Retina Consultants - Santa Maria | Santa Maria | California | 93454 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Retina Consultants of Southern Colorado PC | Colorado Springs | Colorado | 80909 | — |
| Southwest Retina Consultants | Durango | Colorado | 81303 | — |
| Colorado Retina Associates, PC | Lakewood | Colorado | 80228 | — |
| Rand Eye | Deerfield Beach | Florida | 33064 | — |
| Florida Eye Associates - Melbourne 2nd Office | Melbourne | Florida | 32901 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Vitreous Assoc of FL | St. Petersburg | Florida | 33711 | — |
| Southern Vitreoretinal Associates | Tallahassee | Florida | 32308 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina PC | Marietta | Georgia | 30060-1137 | — |
| Illinois Eye and Ear Infirmary | Chicago | Illinois | 60612 | — |
| University Retina and Macula Associates, PC | Oak Forest | Illinois | 60452 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Vitreo Retinal Consultants | Wichita | Kansas | 67214 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Johns Hopkins Hospital. | Baltimore | Maryland | 21287 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740-5940 | — |
| Mass Eye and Ear Infirmary | Boston | Massachusetts | 02114 | — |
| Vitreo-Retinal Associates | Grand Rapids | Michigan | 49546 | — |
| Associated Retinal Consultants PC | Royal Oak | Michigan | 48073 | — |
| VitreoRetinal Surgery, PLLC.; DBA Retina Consultants of Minnesota | Edina | Minnesota | 55435 | — |
| Midwest Vision Research Foundation | Chesterfield | Missouri | 63017 | — |
| The Retina Institute | St Louis | Missouri | 63128 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Mid Atlantic Retina | Cherry Hill | New Jersey | 08034 | — |
| Retina Associates of NJ | Teaneck | New Jersey | 07666 | — |
| Retina Vitreous Center, PA | Toms River | New Jersey | 08755 | — |
| Long Is. Vitreoretinal Consult | Hauppauge | New York | 11788 | — |
| Ophthalmic Consultants of Long Island | Oceanside | New York | 11572 | — |
| Retina Associates of Western New York | Rochester | New York | 14620 | — |
| The Retina Consultants | Slingerlands | New York | 12159 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Charlotte Eye Ear Nose and Throat Associates PA | Charlotte | North Carolina | 28210 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Retina Assoc of Cleveland Inc | Cleveland | Ohio | 44122 | — |
| Cleveland Clinic Foundation; Cole Eye Institute | Cleveland | Ohio | 44195-0001 | — |
| Ohio State University | Columbus | Ohio | 43212-3153 | — |
| Retina Associates of Cleveland - Middleburg Heights Location | Middleburg Heights | Ohio | 44130 | — |
| Retina Associates of Cleveland - Youngstown Location | Youngstown | Ohio | 44505 | — |
| Casey Eye Institute | Portland | Oregon | 97239 | — |
| Mid Atlantic Retina - Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | — |
| Southeastern Retina Associates Chattanooga | Chattanooga | Tennessee | 37421 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| Retina Res Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Retina Associates | Austin | Texas | 78705-1169 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384-4167 | — |
| Retina Consultants of Houston | The Woodlands | Texas | 77384 | — |
| Rocky Mountain Retina | Salt Lake City | Utah | 84107 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
| University of Wisconsin | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03972709, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2024 · Synced Sep 4, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03972709 live on ClinicalTrials.gov.