Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen
Public ClinicalTrials.gov record NCT03974932. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3b, Open-Label Study of HTX-011 as Part of a Scheduled Non-Opioid Multimodal Analgesic Regimen in Subjects Undergoing Total Knee Arthroplasty
Study identification
- NCT ID
- NCT03974932
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Heron Therapeutics
- Industry
- Enrollment
- 116 participants
Conditions and interventions
Conditions
Interventions
- HTX-011 Drug
- Ibuprofen Drug
- Acetaminophen Drug
- Celecoxib Drug
- +/- Bupivacaine HCl Drug
- Luer Lock Applicator Device
Drug · Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2019
- Primary completion
- Dec 6, 2020
- Completion
- Jan 6, 2021
- Last update posted
- Mar 1, 2026
2019 – 2021
United States locations
- U.S. sites
- 6
- U.S. states
- 4
- U.S. cities
- 6
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Helen Keller Hospital | Sheffield | Alabama | 35660 | — |
| Phoenix Clinical Research, LLC | Tamarac | Florida | 33321 | — |
| Midwest Clinical Research Center, LLC | Dayton | Ohio | 45417 | — |
| First Surgical Hospital | Bellaire | Texas | 77401 | — |
| Plano Surgical Hospital | Plano | Texas | 75093 | — |
| Endeavor Clinical Trials, LLC. | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03974932, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 1, 2026 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03974932 live on ClinicalTrials.gov.