Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
Public ClinicalTrials.gov record NCT03977155. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Tolerability of BOS-589 in the Treatment of Patients With Diarrhea-predominant Irritable Bowel Syndrome (IBS-D)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is being conducted to evaluate in participants with diarrhea-predominant Irritable Bowel Syndrome (IBS-D) the abdominal pain response to BOS-589 after 4 weeks of treatment and to evaluate the overall safety and tolerability of BOS-589 in the treatment of IBS-D during 4 weeks of treatment, relative to placebo (PBO).
Study identification
- NCT ID
- NCT03977155
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 133 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 4, 2019 (Actual)
- Primary completion
- May 6, 2020 (Actual)
- Completion
- May 6, 2020 (Actual)
- Last update posted
- Jun 7, 2021
2019 – 2020
United States locations
- U.S. sites
- 58
- U.S. states
- 23
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Clinical Research Associates | Huntsville | Alabama | 35801 | — |
| Synexus Clinical Research US, Inc. - East Valley Family Physicians, PLC | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - Phoenix Southeast | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - Desert Clinical Research, LLC | Mesa | Arizona | 85018 | — |
| Synexus Clinical Research US, Inc. - Central Arizona Medical Associates, PC | Mesa | Arizona | 85213 | — |
| Hope Research Institute LLC | Peoria | Arizona | 85381 | — |
| Elite Clinical Studies | Phoenix | Arizona | 85018 | — |
| Synexus Clinical Research US, Inc. - Tatum Highlands Medical Associates, PLLC | Phoenix | Arizona | 85050 | — |
| Hope Research Institute LLC | Phoenix | Arizona | 85206 | — |
| Arkansas Gastroenterology | North Little Rock | Arkansas | 72117 | — |
| Synexus Clinical Research US, Inc. | Carlsbad | California | 95821 | — |
| Paragon Rx Clinical, Inc. | Garden Grove | California | 92683 | — |
| eStudySite | La Mesa | California | 91942 | — |
| Grossmont Center For Clinical Research | La Mesa | California | 92008 | — |
| Clinical Trials Research | Sacramento | California | 91942 | — |
| Research and Education Inc | San Diego | California | 92105 | — |
| Precision Research Institute | San Diego | California | 92114 | — |
| Shahram Jacobs MD Inc | Sherman Oaks | California | 91403 | — |
| Millennium ClinicalTrials | Thousand Oaks | California | 92840 | — |
| Advanced Rx Clinical Research | Westminster | California | 91360 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| PAB Clinical Research-ClinEdge-PPDS | Brandon | Florida | 33511 | — |
| Nature Coast Clinical Research LLC - ERN-PPDS | Inverness | Florida | 34452 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Health Awareness Inc | Jupiter | Florida | 33458 | — |
| Suncoast Research Group LLC - ERN-PPDS | Miami | Florida | 33135 | — |
| Ormond Medical Arts Pharmaceutical | Ormond Beach | Florida | 32174 | — |
| Precision Clinical Research, LLC | Sunrise | Florida | 33351 | — |
| Northwest Clinical Trials-ClinEdge-PPDS | Boise | Idaho | 83704 | — |
| Synexus Clinical Research US, Inc. - Allaw | Evansville | Indiana | 47714 | — |
| Boston Clinical Trials Inc | Boston | Massachusetts | 02131 | — |
| West Michigan Clinical Research | Wyoming | Michigan | 49519 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Quality Clinical Research - ClinEdge - PPDS | Omaha | Nebraska | 68114 | — |
| Albuquerque Clinical Trials Inc - BTC - PPDS | Albuquerque | New Mexico | 87102 | — |
| NY Scientific | Brooklyn | New York | 11235 | — |
| Peters Medical Research, LLC | High Point | North Carolina | 27262 | — |
| PMG Research of Raleigh, LLC | Raleigh | North Carolina | 27609 | — |
| Synexus Clinical Research US, Inc. | Akron | Ohio | 44311 | — |
| Hometown Urgent Care and Research | Cincinnati | Ohio | 45215 | — |
| Synexus Clinical Research US, Inc. | Columbus | Ohio | 45424 | — |
| Hometown Urgent Care and Research | Dayton | Ohio | 43212 | — |
| Founders Research Corporation | Philadelphia | Pennsylvania | 19114 | — |
| Preferred Primary Care Physicians | Uniontown | Pennsylvania | 15401 | — |
| Safe Harbor Clinical Research | East Providence | Rhode Island | 02914 | — |
| Synexus Clinical Research US, Inc. | Anderson | South Carolina | 29621 | — |
| Pledmont Research Partners LLC | Fort Mill | South Carolina | 29707 | — |
| Synexus Clinical Research US, Inc. | Greer | South Carolina | 29651 | — |
| WR-ClinSearch, LLC | Chattanooga | Tennessee | 37909 | — |
| New Phase Research & Development | Knoxville | Tennessee | 37421 | — |
| L12 Clinical Research | Dallas | Texas | 75219 | — |
| Synexus Clinical Research US, Inc. | Dallas | Texas | 78209 | — |
| Southwest Clinical Trials | Houston | Texas | 77074 | — |
| Quality Research Inc. | San Antonio | Texas | 75234 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Blue Ridge Medical Research | Lynchburg | Virginia | 24502 | — |
| Clinical Research Partners LLC | Richmond | Virginia | 23235 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03977155, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2021 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03977155 live on ClinicalTrials.gov.