A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older
Public ClinicalTrials.gov record NCT03982199. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Double-blind, Placebo-controlled Phase 2b Study to Assess the Efficacy, Immunogenicity and Safety of an Ad26.RSV.preF-based Regimen in the Prevention of RT PCR-confirmed RSV-mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to demonstrate the efficacy of active study vaccine in the prevention of reverse transcriptase polymerase chain reaction (RT-PCR) confirmed respiratory syncytial virus (RSV)-mediated lower respiratory tract disease (LRTD), when compared to placebo.
Study identification
- NCT ID
- NCT03982199
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 5,815 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1, 2019 (Actual)
- Primary completion
- Jun 6, 2022 (Actual)
- Completion
- May 26, 2023 (Actual)
- Last update posted
- May 25, 2025
2019 – 2023
United States locations
- U.S. sites
- 40
- U.S. states
- 21
- U.S. cities
- 38
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Optimal Research | Huntsville | Alabama | 35802 | — |
| Synexus Clinical Research US Inc | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US Inc | Phoenix | Arizona | 85018 | — |
| Central Phoenix Medical Clinic | Phoenix | Arizona | 85020 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Paradigm Clinical Research Centers, Inc. | Redding | California | 96001 | — |
| Benchmark Research | Sacramento | California | 95684 | — |
| Optimal Research | San Diego | California | 92108 | — |
| Synexus Clinical Research US Inc | Aurora | Colorado | 80014 | — |
| Lynn Institute | Colorado Springs | Colorado | 80920 | — |
| Optimal Research | Melbourne | Florida | 32934 | — |
| Advanced Clinical Research | Boise | Idaho | 83642 | — |
| Optimal Research | Peoria | Illinois | 61614 | — |
| Synexus Clinical Research US Inc | Evansville | Indiana | 47714 | — |
| The Iowa Clinic | West Des Moines | Iowa | 50266 | — |
| Hutchinson Clinic | Hutchinson | Kansas | 67502 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219 | — |
| Heartland Research Associates, LLC | Newton | Kansas | 67114 | — |
| Heartland Research Associates, LLC | Wichita | Kansas | 67205 | — |
| Optimal Research | Rockville | Maryland | 20850 | — |
| Synexus Clinical Research US Inc | Richfield | Minnesota | 55432 | — |
| The Center For Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Synexus Clinical Research US Inc | St Louis | Missouri | 63141 | — |
| Synexus Clinical Research US Inc | Elkhorn | Nebraska | 68022 | — |
| Synexus Clinical Research US Inc | Omaha | Nebraska | 68144 | — |
| United Medical Associates | Binghamton | New York | 13901 | — |
| Regional Clinical Research, Inc. | Endwell | New York | 13760 | — |
| University of Rochester / Rochester General Hospital | Rochester | New York | 14621 | — |
| Synexus Clinical Research US Inc | Akron | Ohio | 44311 | — |
| Synexus Clinical Research US Inc | Cincinnati | Ohio | 45236 | — |
| Rapid Medical Research | Cleveland | Ohio | 44122 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Omega Medical Research | Warwick | Rhode Island | 02886 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Optimal Research | Austin | Texas | 78705 | — |
| Ventavia Research Group, LLC | Fort Worth | Texas | 76104 | — |
| Synexus Clinical Research US Inc | Murray | Utah | 84123 | — |
| Advanced Clinical Research | Salt Lake City | Utah | 84123 | — |
| Advanced Clinical Research | West Jordan | Utah | 84088 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03982199, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 25, 2025 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03982199 live on ClinicalTrials.gov.