A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye
Public ClinicalTrials.gov record NCT03982368. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A 4 Weeks, Phase II, Multicenter, Randomized, Double-masked, Vehicle-controlled, Parallel Group Study With 12 Weeks of Follow-up to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution vs Vehicle in Moderate to Severe Dry Eye.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this study is to assess the efficacy and safety of rhNGF eye drops at 20 μg/ml concentration administered two or three times daily for 4 weeks in patients with moderate to severe dry eye.
Study identification
- NCT ID
- NCT03982368
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 261 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 10, 2019 (Actual)
- Primary completion
- Jul 15, 2020 (Actual)
- Completion
- Jul 15, 2020 (Actual)
- Last update posted
- Apr 19, 2024
2019 – 2020
United States locations
- U.S. sites
- 12
- U.S. states
- 7
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Global Research Management | Glendale | California | 91204 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| Martel Eye Medical Group | Rancho Cordova | California | 95670 | — |
| Sierra Clinical Trials & Research Organization | Santa Ana | California | 92647 | — |
| Clayton Eye Clinical Research, LLC | Morrow | Georgia | 30260 | — |
| Kentucky Eye Institute | Lexington | Kentucky | 40517 | — |
| Tauber Eye Center | Kansas City | Missouri | 64111 | — |
| Moyes Eye Center | Kansas City | Missouri | 64154 | — |
| SightMD | Babylon | New York | 11702 | — |
| Toyos Clinic | Nashville | Tennessee | 37027 | — |
| Houston Eye Associates HEA - Gramercy Location | Houston | Texas | 77025 | — |
| Advanced Laser Vision Surgical Institute (Study Site) Intouch Clinical Research Center (SMO) | Houston | Texas | 77034 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03982368, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 19, 2024 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03982368 live on ClinicalTrials.gov.