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Completed Phase 2 Interventional Results available

A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver Damage

ClinicalTrials.gov ID: NCT03987451

Public ClinicalTrials.gov record NCT03987451. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 8:12 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Investigation of Efficacy and Safety of Semaglutide s.c. Once-weekly Versus Placebo in Subjects With Non-alcoholic Steatohepatitis and Compensated Liver Cirrhosis

Study identification

NCT ID
NCT03987451
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Novo Nordisk A/S
Industry
Enrollment
71 participants

Conditions and interventions

Interventions

  • Semaglutide Drug
  • Placebo (semaglutide) Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 17, 2019
Primary completion
Apr 21, 2021
Completion
Jun 9, 2021
Last update posted
May 28, 2024

2019 – 2021

United States locations

U.S. sites
24
U.S. states
13
U.S. cities
24
Facility City State ZIP Site status
Arizona Liver Health Chandler Arizona 85224
The Institute for Liver Health dba Arizona Liver Health Peoria Arizona 85381
Southern California Research Center Coronado California 92118
Altman Clinical Translational Research Institute La Jolla California 92037
Inland Empire Clinical Trials LLC Rialto California 92377
Excel Medical Center Clinical Trials, LLC Boca Raton Florida 33434
University of Florida-CTRB Gainesville Florida 32610
University of Miami/Schiff Center for Liver Diseases Miami Florida 33136
Piedmont Research Institute Atlanta Georgia 30309
Gastrointestinal Specialists of Georgia Marietta Georgia 30060
Indiana University Indianapolis Indiana 46202
Digestive Research Alliance of Michiana South Bend Indiana 46635
University of Kentucky Hospital Lexington Kentucky 40508
Mercy Medical Center, GI Research Baltimore Maryland 21202
Massachusetts General Hospital Boston Massachusetts 02114
Henry Ford Hospital Detroit Michigan 48202
Duke University Durham North Carolina 27710
Gastroenterology Center For The Mid-South Germantown Tennessee 38138
Digestive Health Research - Tristar Summit Medical Center Hermitage Tennessee 37076
Quality Medical Research Nashville Tennessee 37211
Texas Clinical Research Institute, LLC Arlington Texas 76012
The University of Texas Southwestern Medical Center - Dallas Dallas Texas 75390-8887
American Research Corporation at the Texas Liver Institute San Antonio Texas 78215
VCU Health Systems Richmond Virginia 23298

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03987451, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 28, 2024 · Synced Jul 24, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03987451 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →