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Recruiting Phase 1 Interventional

Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

ClinicalTrials.gov ID: NCT03988283

Public ClinicalTrials.gov record NCT03988283. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 21, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Pilot Study to Assess the Safety, Feasibility, and Preliminary Efficacy of a Neoepitope-based Personalized DNA Vaccine Approach in Pediatric Patients With Recurrent Central Nervous System Tumors

Study identification

NCT ID
NCT03988283
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Washington University School of Medicine
Other
Enrollment
7 participants

Conditions and interventions

Interventions

  • Papivax Biotech TDS-IM v2.0 Device
  • Peripheral blood draw Procedure
  • Personalized neoantigen DNA vaccine Biological

Device · Procedure · Biological

Eligibility (public fields only)

Age range
Up to 25 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 1, 2024
Primary completion
Mar 30, 2029
Completion
Feb 27, 2031
Last update posted
May 6, 2026

2024 – 2031

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Washington University School of Medicine St Louis Missouri 63110 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03988283, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 6, 2026 · Synced May 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03988283 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →