A Research Study to Compare Two Doses of Semaglutide Taken Once Weekly in People With Type 2 Diabetes
Public ClinicalTrials.gov record NCT03989232. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Semaglutide 2.0 mg s.c. Once-weekly Compared to Semaglutide 1.0 mg s.c. Once-weekly in Subjects With Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study compares the effect of two doses of semaglutide (1.0 mg and 2.0 mg) in people with type 2 diabetes (T2D). People taking part in the study will take the medicine together with their current diabetes medicine (sulphonylurea and/or metformin). Participants will get a dose of either 1.0 mg or 2.0 mg semaglutide once a week - which dose is decided by chance. Participants will inject semaglutide under the skin once a week. The study will last for about 49 weeks. Participants will have 9 clinic visits and 2 phone calls with the study doctor. At the visits participants will have blood taken and eye tests done. Women cannot take part if pregnant, breast-feeding or planning to become pregnant during the study period. Female participants who can get pregnant will be checked 11 times for pregnancy via urine tests.
Study identification
- NCT ID
- NCT03989232
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 961 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 19, 2019 (Actual)
- Primary completion
- Sep 18, 2020 (Actual)
- Completion
- Nov 9, 2020 (Actual)
- Last update posted
- Feb 13, 2023
2019 – 2020
United States locations
- U.S. sites
- 61
- U.S. states
- 24
- U.S. cities
- 58
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Novo Nordisk Investigational Site | Birmingham | Alabama | 35205 | — |
| Novo Nordisk Investigational Site | Chandler | Arizona | 85224 | — |
| Novo Nordisk Investigational Site | Glendale | Arizona | 85306 | — |
| Novo Nordisk Investigational Site | Glendale | Arizona | 85308 | — |
| Novo Nordisk Investigational Site | Mesa | Arizona | 85213 | — |
| Novo Nordisk Investigational Site | Phoenix | Arizona | 85050 | — |
| Novo Nordisk Investigational Site | Buena Park | California | 90620 | — |
| Novo Nordisk Investigational Site | Fresno | California | 93720 | — |
| Novo Nordisk Investigational Site | Los Angeles | California | 90057 | — |
| Novo Nordisk Investigational Site | San Diego | California | 92103 | — |
| Novo Nordisk Investigational Site | Spring Valley | California | 91978 | — |
| Novo Nordisk Investigational Site | Walnut Creek | California | 94598 | — |
| Novo Nordisk Investigational Site | West Hills | California | 91304 | — |
| Novo Nordisk Investigational Site | Colorado Springs | Colorado | 80906 | — |
| Novo Nordisk Investigational Site | Coral Gables | Florida | 33134 | — |
| Novo Nordisk Investigational Site | Hollywood | Florida | 33024 | — |
| Novo Nordisk Investigational Site | Jacksonville | Florida | 32216 | — |
| Novo Nordisk Investigational Site | Adairsville | Georgia | 30103 | — |
| Novo Nordisk Investigational Site | Alpharetta | Georgia | 30022 | — |
| Novo Nordisk Investigational Site | Roswell | Georgia | 30076 | — |
| Novo Nordisk Investigational Site | Meridian | Idaho | 83646 | — |
| Novo Nordisk Investigational Site | Carlinville | Illinois | 62626 | — |
| Novo Nordisk Investigational Site | Chicago | Illinois | 60607 | — |
| Novo Nordisk Investigational Site | Peoria | Illinois | 61603 | — |
| Novo Nordisk Investigational Site | Topeka | Kansas | 66606 | — |
| Novo Nordisk Investigational Site | Lexington | Kentucky | 40503 | — |
| Novo Nordisk Investigational Site | Louisville | Kentucky | 40213 | — |
| Novo Nordisk Investigational Site | Lake Charles | Louisiana | 70601 | — |
| Novo Nordisk Investigational Site | Sterling Heights | Michigan | 48310-3503 | — |
| Novo Nordisk Investigational Site | Jefferson City | Missouri | 65109 | — |
| Novo Nordisk Investigational Site | Butte | Montana | 59701 | — |
| Novo Nordisk Investigational Site | Trenton | New Jersey | 08611 | — |
| Novo Nordisk Investigational Site | New Windsor | New York | 12553 | — |
| Novo Nordisk Investigational Site | Chapel Hill | North Carolina | 27514 | — |
| Novo Nordisk Investigational Site | Greensboro | North Carolina | 27408 | — |
| Novo Nordisk Investigational Site | Salisbury | North Carolina | 28144 | — |
| Novo Nordisk Investigational Site | Statesville | North Carolina | 28625 | — |
| Novo Nordisk Investigational Site | Wilmington | North Carolina | 28401 | — |
| Novo Nordisk Investigational Site | Columbus | Ohio | 43213 | — |
| Novo Nordisk Investigational Site | Mason | Ohio | 45040-6815 | — |
| Novo Nordisk Investigational Site | Norman | Oklahoma | 73069 | — |
| Novo Nordisk Investigational Site | Corvallis | Oregon | 97330-3737 | — |
| Novo Nordisk Investigational Site | Gaffney | South Carolina | 29341 | — |
| Novo Nordisk Investigational Site | Greenville | South Carolina | 29615 | — |
| Novo Nordisk Investigational Site | Chattanooga | Tennessee | 37404 | — |
| Novo Nordisk Investigational Site | Kingsport | Tennessee | 37660 | — |
| Novo Nordisk Investigational Site | Memphis | Tennessee | 38119 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75230 | — |
| Novo Nordisk Investigational Site | Dallas | Texas | 75390-9302 | — |
| Novo Nordisk Investigational Site | Houston | Texas | 77074 | — |
| Novo Nordisk Investigational Site | Humble | Texas | 77338 | — |
| Novo Nordisk Investigational Site | Hurst | Texas | 76054 | — |
| Novo Nordisk Investigational Site | Katy | Texas | 77450 | — |
| Novo Nordisk Investigational Site | Plano | Texas | 75075 | — |
| Novo Nordisk Investigational Site | San Antonio | Texas | 78229 | — |
| Novo Nordisk Investigational Site | San Antonio | Texas | 78230 | — |
| Novo Nordisk Investigational Site | Shavano Park | Texas | 78231 | — |
| Novo Nordisk Investigational Site | Sugar Land | Texas | 77479 | — |
| Novo Nordisk Investigational Site | Olympia | Washington | 98502 | — |
| Novo Nordisk Investigational Site | Walla Walla | Washington | 99362-4445 | — |
| Novo Nordisk Investigational Site | Wenatchee | Washington | 98801-2028 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 68 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03989232, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 13, 2023 · Synced Oct 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT03989232 live on ClinicalTrials.gov.