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Completed Phase 2 Interventional

Vopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial Cancer

ClinicalTrials.gov ID: NCT03989362

Public ClinicalTrials.gov record NCT03989362. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 4:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Multicenter Trial of ICOS Agonist Monoclonal Antibody (mAb) Vopratelimab (JTX -2011) and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Adult Subjects With Non-small Cell Lung Cancer or Urothelial Cancer

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

JTX-2011-201 is a Phase 2, open label clinical study of vopratelimab (JTX-2011) and ipilimumab in adult subjects with non-small cell lung cancer (NSCLC) or urothelial cancer to evaluate safety and efficacy.

Study identification

NCT ID
NCT03989362
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Jounce Therapeutics, Inc.
Industry
Enrollment
61 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 5, 2019
Primary completion
Mar 14, 2022
Completion
Mar 14, 2022
Last update posted
Sep 9, 2022

2019 – 2022

United States locations

U.S. sites
18
U.S. states
15
U.S. cities
18
Facility City State ZIP Site status
Beverly Hills Cancer Center Beverly Hills California 90211
University of Southern California Medical Center Los Angeles California 90033
Christiana Care Health Services Newark Delaware 19713
Florida Cancer Specialists Sarasota Cattlemen Sarasota Florida 34232
University of Maryland - Marlene and Stewart Greenebaum Cancer Center Baltimore Maryland 21201
Massachusetts General Hospital Boston Massachusetts 02114
Washington University School of Medicine St Louis Missouri 63110
The Valley Hospital Ridgewood New Jersey 07450
Weill Cornell Medical College New York New York 10065
University of Rochester Rochester New York 14642
Southeastern Medical Oncology Center Clinton North Carolina 28328
Cleveland Clinic Foundation Cleveland Ohio 44195
Allegheny Health Network Research Institute Pittsburgh Pennsylvania 15212
Lifespan Cancer Institute Providence Rhode Island 02903
Vanderbilt University Medical Center Nashville Tennessee 37232
University of Texas MD Anderson Cancer Center Houston Texas 77030
University of The Texas Health Science Center at San Antonio San Antonio Texas 78229
University of Virginia Health System Charlottesville Virginia 22908

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT03989362, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 9, 2022 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT03989362 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →