CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
Public ClinicalTrials.gov record NCT03998163. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter Study to Evaluate the Safety and Effectiveness of Intravenous CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, open-label study to evaluate the safety and effectiveness of intravenous (IV) CR845 at a dose of 0.5 mcg/kg administered after each dialysis session. The study includes an up to 12-week Treatment Period.
Study identification
- NCT ID
- NCT03998163
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 222 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 5, 2019
- Primary completion
- Feb 25, 2020
- Completion
- Mar 5, 2020
- Last update posted
- Oct 14, 2021
2019 – 2020
United States locations
- U.S. sites
- 33
- U.S. states
- 15
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cara Therapeutics Study Site | Escondido | California | 92025 | — |
| Cara Therapeutics Study Site | Riverside | California | 92505 | — |
| Cara Therapeutics Study Site | San Diego | California | 92111 | — |
| Cara Therapeutics Study Site | Victorville | California | 92395 | — |
| Cara Therapeutics Study Site | Denver | Colorado | 80230 | — |
| Cara Therapeutics Study Site | Middlebury | Connecticut | 06762 | — |
| Cara Therapeutics Study Site | Norwich | Connecticut | 06382 | — |
| Cara Therapeutics Study Site | Coral Gables | Florida | 33134 | — |
| Cara Therapeutics Study Site | Fort Lauderdale | Florida | 33308 | — |
| Cara Therapeutics Study Site | Hollywood | Florida | 33024 | — |
| Cara Therapeutics Study Site | Miami | Florida | 33169 | — |
| Cara Therapeutics Study Site 2 | Tampa | Florida | 33614 | — |
| Cara Therapeutics Study Site | Tampa | Florida | 33614 | — |
| Cara Therapeutics Study Site | Albany | Georgia | 31701 | — |
| Cara Therapeutics Study Site | Boston | Massachusetts | 02111 | — |
| Cara Therapeutics Study Site | Roseville | Michigan | 48066 | — |
| Cara Therapeutics Study Site | Minneapolis | Minnesota | 55404 | — |
| Cara Therapeutics Study Site | Kansas City | Missouri | 64131 | — |
| Cara Therapeutics Study Site | Las Vegas | Nevada | 89106 | — |
| Cara Therapeutics Study Site 2 | Las Vegas | Nevada | 89128 | — |
| Cara Therapeutics Study Site | Great Neck | New York | 11021 | — |
| Cara Therapeutics Study Site | Philadelphia | Pennsylvania | 19140 | — |
| Cara Therapeutics Study Site | Spartanburg | South Carolina | 29302 | — |
| Cara Therapeutics Study Site | Knoxville | Tennessee | 37920 | — |
| Cara Therapeutics Study Site | Austin | Texas | 78751 | — |
| Cara Therapeutics Study Site | Duncanville | Texas | 75137 | — |
| Cara Therapeutics Study Site | Greenville | Texas | 75402 | — |
| Cara Therapeutics Study Site | Mansfield | Texas | 76063 | — |
| Cara Therapeutics Study Site | Mesquite | Texas | 75080 | — |
| Cara Therapeutics Study Site 2 | San Antonio | Texas | 78221 | — |
| Cara Therapeutics Study Site | San Antonio | Texas | 78251 | — |
| Cara Therapeutics Study Site 3 | San Antonio | Texas | 78258 | — |
| Cara Therapeutics Study Site | Temple | Texas | 76502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT03998163, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2021 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT03998163 live on ClinicalTrials.gov.