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Active, not recruiting Phase 3 Interventional Results available

A Study of Nivolumab, Nivolumab Plus Ipilimumab, or Investigator's Choice Chemotherapy for the Treatment of Participants With Deficient Mismatch Repair (dMMR)/Microsatellite Instability High (MSI-H) Metastatic Colorectal Cancer (mCRC)

ClinicalTrials.gov ID: NCT04008030

Public ClinicalTrials.gov record NCT04008030. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 7:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Randomized Clinical Trial of Nivolumab Alone, Nivolumab in Combination With Ipilimumab, or Investigator's Choice Chemotherapy in Participants With Microsatellite Instability High (MSI-H) or Mismatch Repair Deficient (dMMR) Metastatic Colorectal Cancer

Study identification

NCT ID
NCT04008030
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
839 participants

Conditions and interventions

Interventions

  • Ipilimumab Biological
  • Oxaliplatin Drug
  • Leucovorin Drug
  • Fluorouracil Drug
  • Irinotecan Drug
  • Bevacizumab Drug
  • Cetuximab Drug
  • Nivolumab Biological

Biological · Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 4, 2019
Primary completion
Aug 27, 2024
Completion
Jun 9, 2026
Last update posted
Oct 2, 2025

2019 – 2026

United States locations

U.S. sites
9
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
Local Institution - 0059 Los Angeles California 90033
Local Institution - 0130 Sacramento California 95817
Local Institution - 0103 Denver Colorado 80218
Local Institution - 0119 Arlington Heights Illinois 60005
Local Institution - 0060 New York New York 10065
Local Institution - 0105 Portland Oregon 97227
Local Institution - 0121 Pittsburgh Pennsylvania 15232
Local Institution - 0106 Dallas Texas 75246
Local Institution - 0104 Roanoke Virginia 24014

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 148 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04008030, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 2, 2025 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04008030 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →