A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor
Public ClinicalTrials.gov record NCT04008797. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label Study of E7386 in Combination With Other Anticancer Drug(s) in Subjects With Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to assess the safety and tolerability and to determine the recommended Phase 2 dose (RP2D) of E7386 in combination with other anticancer drug(s), and to determine the optimal dose of E7386 in combination with lenvatinib in endometrial carcinoma (EC) (for EC Dose Optimization Part only).
Study identification
- NCT ID
- NCT04008797
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 301 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 11, 2019 (Actual)
- Primary completion
- Mar 31, 2027 (Estimated)
- Completion
- Mar 31, 2027 (Estimated)
- Last update posted
- Oct 14, 2026
2019 – 2027
United States locations
- U.S. sites
- 28
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAMS | Little Rock | Arkansas | 72205-7199 | — |
| University of California San Diego (UCSD) - Moores Cancer Center(All) | La Jolla | California | 92037 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Pasadena Liver Center | Pasadena | California | 91105 | — |
| California Pacific Medical Center | San Francisco | California | 94066 | — |
| UCLA University of California - Los Angeles | Santa Monica | California | 90404 | — |
| John Muir Clinical Research | Walnut Creek | California | 94598 | — |
| University of Colorado Cancer Center - Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| Uni. Of Miami- Sylvester Cancer Centre | Miami | Florida | 33136 | — |
| Florida Cancer Specialists - South | Sarasota | Florida | 34236 | — |
| Florida Cancer Specialists - East | West Palm Beach | Florida | 33401 | — |
| Women's Cancer Care - Covington, LA | Covington | Louisiana | 70433 | — |
| University Of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | — |
| Perlmutter Cancer Center- NYU Langone Health | New York | New York | 10016 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | — |
| Montefiore Medical Center (MMC) - Jack D. Weiler Hospital | The Bronx | New York | 10461 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | — |
| University of Oklahoma Health Science Center | Oklahoma City | Oklahoma | 73104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Sanford Cancer Centre | Sioux Falls | South Dakota | 57106 | — |
| Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center (VUMC) - Vanderbilt-Ingram Cancer Center (VICC) - Nashville | Nashville | Tennessee | 37232 | — |
| Mary Crowley Cancer Research | Dallas | Texas | 75230 | — |
| University of Texas Southwestern Medical | Dallas | Texas | 75390 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Fred Hutchinson/University of Washington Cancer Consortium | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04008797, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04008797 live on ClinicalTrials.gov.