A Study of Nivolumab and Ipilimumab in Untreated Participants With Stage 3 Non-small Cell Lung Cancer (NSCLC) That is Unable or Not Planned to be Removed by Surgery
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This page only displays public information reproduced from the official ClinicalTrials.gov record NCT04026412. It adds no medical advice, opinions, or eligibility judgments. The official record remains the source of truth for eligibility criteria, enrollment, and contact information.
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Official title
A Phase 3, Randomized, Open Label Study to Compare Nivolumab Plus Concurrent Chemoradiotherapy (CCRT) Followed by Nivolumab Plus Ipilimumab or Nivolumab Plus CCRT Followed by Nivolumab vs CCRT Followed by Durvalumab in Previously Untreated, Locally Advanced Non-small Cell Lung Cancer (LA NSCLC)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the study is to compare the effectiveness of nivolumab plus concurrent chemoradiotherapy (CCRT) followed by nivolumab plus ipilimumab vs CCRT followed by durvalumab in participants with untreated Locally Advanced Non-small Cell Lung Cancer (LA NSCLC).
Study identification
- NCT ID
- NCT04026412
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 925 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 8, 2019 (Actual)
- Primary completion
- Mar 22, 2024 (Actual)
- Completion
- Nov 26, 2024 (Actual)
- Last update posted
- Jul 24, 2025
2019 – 2024
United States locations
- U.S. sites
- 24
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0119 | La Jolla | California | 92093 | — |
| Local Institution - 0207 | San Francisco | California | 94115 | — |
| Local Institution - 0166 | San Francisco | California | 94143 | — |
| Local Institution - 0129 | Lone Tree | Colorado | 80124 | — |
| Local Institution - 0233 | Jacksonville | Florida | 32207 | — |
| Local Institution - 0219 | Orlando | Florida | 32804 | — |
| Local Institution - 0039 | Pensacola | Florida | 32504 | — |
| Local Institution - 0125 | Atlanta | Georgia | 30322 | — |
| Local Institution - 0165 | Augusta | Georgia | 30912 | — |
| Local Institution - 0218 | Edgewood | Kentucky | 41017 | — |
| Local Institution - 0108 | Bethesda | Maryland | 20817 | — |
| Local Institution - 0116 | Traverse City | Michigan | 49684 | — |
| Local Institution - 0053 | Cincinnati | Ohio | 45220 | — |
| Local Institution - 0131 | Cincinnati | Ohio | 45242 | — |
| Local Institution - 0188 | Cincinnati | Ohio | 45267 | — |
| Local Institution - 0112 | Cleveland | Ohio | 44106 | — |
| Local Institution - 0124 | Cleveland | Ohio | 44106 | — |
| Local Institution - 0047 | Cleveland | Ohio | 44109 | — |
| Local Institution - 0123 | Youngstown | Ohio | 44501 | — |
| Local Institution - 0077 | Charleston | South Carolina | 29414 | — |
| Local Institution - 0191 | Austin | Texas | 78731 | — |
| Local Institution - 0079 | Bryan | Texas | 77802 | — |
| Local Institution - 0130 | Dallas | Texas | 75203 | — |
| Local Institution - 0071 | Burlington | Vermont | 05405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 159 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04026412, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2025 · Synced Nov 15, 2026
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