Induction FLOT With CROSS CRT for Esophageal Cancer
Public ClinicalTrials.gov record NCT04028167. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase II Study of Induction FLOT Followed by Neoadjuvant Chemoradiation in Patients With Resectable Adenocarcinoma of the Esophagus or Gastroesophageal Junction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study evaluates a novel regimen of induction chemotherapy using a combination of docetaxel, oxaliplatin, and leucovorin, with short term infusional 5-FU (FLOT), given prior to chemoradiotherapy with concurrent carboplatin and paclitaxel, as neoadjuvant therapy prior to definitive surgical resection for patients with adenocarcinoma of the esophagus or gastroesophageal junction
Study identification
- NCT ID
- NCT04028167
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 40 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 7, 2020
- Primary completion
- Jan 1, 2026
- Completion
- Apr 18, 2027
- Last update posted
- Jan 8, 2026
2020 – 2027
United States locations
- U.S. sites
- 7
- U.S. states
- 1
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| UCHealth Southern Colorado - Memorial Hospital Central | Colorado Springs | Colorado | 80909 | — |
| UCHealth Southern Colorado - Memorial Hospital North | Colorado Springs | Colorado | 80920 | — |
| UCHealth Northern Colorado - Poudre Valley Hospital | Fort Collins | Colorado | 80524 | — |
| UCHealth Northern Colorado - Harmony Campus | Fort Collins | Colorado | 80528 | — |
| UCHealth Northern Colorado - Greeley Hospital | Greeley | Colorado | 80634 | — |
| UCHealth Northern Colorado Medical Center of the Rockies | Loveland | Colorado | 80538 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04028167, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 8, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04028167 live on ClinicalTrials.gov.