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Active, not recruiting Phase 2 Interventional

Induction FLOT With CROSS CRT for Esophageal Cancer

ClinicalTrials.gov ID: NCT04028167

Public ClinicalTrials.gov record NCT04028167. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 11:30 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Study of Induction FLOT Followed by Neoadjuvant Chemoradiation in Patients With Resectable Adenocarcinoma of the Esophagus or Gastroesophageal Junction

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study evaluates a novel regimen of induction chemotherapy using a combination of docetaxel, oxaliplatin, and leucovorin, with short term infusional 5-FU (FLOT), given prior to chemoradiotherapy with concurrent carboplatin and paclitaxel, as neoadjuvant therapy prior to definitive surgical resection for patients with adenocarcinoma of the esophagus or gastroesophageal junction

Study identification

NCT ID
NCT04028167
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Enrollment
40 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 100 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 8, 2020 (Actual)
Primary completion
Jan 2, 2026 (Actual)
Completion
Apr 19, 2027 (Estimated)
Last update posted
Jan 9, 2026

2020 – 2027

United States locations

U.S. sites
7
U.S. states
1
U.S. cities
5
Facility City State ZIP Site status
University of Colorado Hospital Aurora Colorado 80045 —
UCHealth Southern Colorado - Memorial Hospital Central Colorado Springs Colorado 80909 —
UCHealth Southern Colorado - Memorial Hospital North Colorado Springs Colorado 80920 —
UCHealth Northern Colorado - Poudre Valley Hospital Fort Collins Colorado 80524 —
UCHealth Northern Colorado - Harmony Campus Fort Collins Colorado 80528 —
UCHealth Northern Colorado - Greeley Hospital Greeley Colorado 80634 —
UCHealth Northern Colorado Medical Center of the Rockies Loveland Colorado 80538 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04028167, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 9, 2026 · Synced Oct 17, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04028167 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →