A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer
Public ClinicalTrials.gov record NCT04031885. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label, Randomized-Controlled Study of Abemaciclib, a CDK4 and 6 Inhibitor, in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer With Visceral Metastases
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The reason for this study is to compare the efficacy of abemaciclib, in combination with fulvestrant, to that of physician's choice of chemotherapy in women with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer that has spread to internal organs. Your participation in this trial could last up to 31 months, depending on your cancer type and how you and your tumor respond.
Study identification
- NCT ID
- NCT04031885
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 4 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 14, 2019 (Actual)
- Primary completion
- Aug 11, 2020 (Actual)
- Completion
- Aug 11, 2020 (Actual)
- Last update posted
- Aug 24, 2021
2019 – 2020
United States locations
- U.S. sites
- 55
- U.S. states
- 26
- U.S. cities
- 54
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale Healthcare Hospitals | Avondale | Arizona | 85392 | — |
| University of Arizona Cancer Center | Phoenix | Arizona | 85004 | — |
| Yuma Regional Cancer Center | Yuma | Arizona | 85364 | — |
| CARTI Cancer Center | Little Rock | Arkansas | 72205 | — |
| Comprehensive Blood and Cancer Center | Bakersfield | California | 93309 | — |
| Compassionate Cancer Care Medical Group Inc | Corona | California | 92879 | — |
| Chan Soon- Shiong Institute for Medicine | Costa Mesa | California | 92627 | — |
| Chan Soon- Shiong Institute for Medicine | El Segundo | California | 90245 | — |
| Compassionate Cancer Care Medical Group Inc | Fountain Valley | California | 92708 | — |
| St. Joseph Heritage Healthcare | Fullerton | California | 92835 | — |
| Scripps Clinic | La Jolla | California | 92037 | — |
| UCLA Medical Center | Los Angeles | California | 90024 | — |
| TRIO - Translational Research in Oncology-US, Inc. | Los Angeles | California | 90095 | — |
| Univ of California Irvine College of Medicine | Orange | California | 92868 | — |
| Comprehensive Cancer Centers of the Desert | Palm Springs | California | 92262 | — |
| Desert Hematology Oncology Medical Group | Rancho Mirage | California | 92270 | — |
| Emad Ibrahim, MD, INC | Redlands | California | 92373 | — |
| Compassionate Cancer Care Medical Group Inc | Riverside | California | 92501 | — |
| University of California, Davis - Health Systems | Sacramento | California | 95864 | — |
| Torrance Memorial Medical Center | Torrance | California | 90505 | — |
| Banner MD Anderson Cancer Center | Greeley | Colorado | 80631 | — |
| Hartford Hospital | Hartford | Connecticut | 06102-5037 | — |
| Millennium Oncology | Hollywood | Florida | 33024 | — |
| Ocala Oncology, P.A. | Ocala | Florida | 34474 | — |
| Tallahassee Memorial Cancer Center | Tallahassee | Florida | 32308 | — |
| Cleveland Clinic of Florida | Weston | Florida | 33331 | — |
| Candler Medical Oncology Practice | Savannah | Georgia | 31405 | — |
| Tift Regional Health System Anita Stewart Oncology Center | Tifton | Georgia | 31794 | — |
| Kaiser Permanente Center for Health Research | Honolulu | Hawaii | 96819 | — |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Cancer Center of Kansas | Wichita | Kansas | 67214 | — |
| Touro Infirmary | New Orleans | Louisiana | 70115 | — |
| Willis-Knighton Cancer Center | Shreveport | Louisiana | 71103 | — |
| York Hospital | York Village | Maine | 03909 | — |
| Reliant Medical Group, Inc. | Worcester | Massachusetts | 01608 | — |
| Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Baptist Cancer Center | Oxford | Mississippi | 38655 | — |
| St. Francis Medical Center | Grand Island | Nebraska | 68803 | — |
| Oncology Hematology West | Omaha | Nebraska | 68130 | — |
| OptumCare Cancer Care | Las Vegas | Nevada | 89102 | — |
| Carol Simon Cancer Center at Overlook Medical Center | Summit | New Jersey | 07901 | — |
| Brooklyn Methodist Hospital | Brooklyn | New York | 11215 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| SUNY At Stony Brook | Stony Brook | New York | 11794 | — |
| White Plains Hospital | White Plains | New York | 10601 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Cancer Care Associates of York | York | Pennsylvania | 17403 | — |
| Womens and Infants | Providence | Rhode Island | 02905 | — |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | — |
| The Center for Cancer and Blood Disorders | Fort Worth | Texas | 76104 | — |
| Oncology Consultants, P.A. | Houston | Texas | 77030 | — |
| Renovatio Clinical | The Woodlands | Texas | 77380 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| Providence Regional Cancer Partnership | Everett | Washington | 98201 | — |
| Cancer Care Northwest | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04031885, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 24, 2021 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04031885 live on ClinicalTrials.gov.