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Completed Phase 3 Interventional

Mono vs. Dual Therapy for Pediatric Pulmonary Arterial Hypertension

ClinicalTrials.gov ID: NCT04039464

Public ClinicalTrials.gov record NCT04039464. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 8:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Kids MoD PAH Trial: Mono- vs. Duo-Therapy for Pediatric Pulmonary Arterial Hypertension

Study identification

NCT ID
NCT04039464
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Johns Hopkins University
Other
Enrollment
28 participants

Conditions and interventions

Interventions

  • Duo-Therapy with Sildenafil + Bosentan Drug
  • Mono-Therapy with Sildenafil Drug

Drug

Eligibility (public fields only)

Age range
3 Months to 18 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2022
Primary completion
Dec 30, 2025
Completion
Dec 30, 2025
Last update posted
Feb 17, 2026

2022 – 2025

United States locations

U.S. sites
10
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
Children's Hospital Colorado Aurora Colorado 80045
Johns Hopkins All Children's Hospital St. Petersburg Florida 33701
Johns Hopkins Medical Institutions Baltimore Maryland 21287
Boston Children's Hospital Boston Massachusetts 02115
Columbia University Medical Center New York New York 10032
New York Medical College Valhalla New York 10595
Vanderbilt University Medical Center Nashville Tennessee 37232
Baylor College of Medicine Houston Texas 77030
Seattle Children's Hospital Seattle Washington 98105
Medical College of Wisconsin Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04039464, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 17, 2026 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04039464 live on ClinicalTrials.gov.

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