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Suspended Phase 1Phase 2 Interventional

A Study to Evaluate Lucitanib in Combination With Nivolumab in Patients With a Solid Tumor

ClinicalTrials.gov ID: NCT04042116

Public ClinicalTrials.gov record NCT04042116. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

LIO-1: A Phase 1b/2, Open-Label Study to Evaluate the Safety and Efficacy of Lucitanib in Combination With Nivolumab in Patients With An Advanced, Metastatic Solid Tumor

Study identification

NCT ID
NCT04042116
Recruitment status
Suspended
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Clovis Oncology, Inc.
Industry
Enrollment
227 participants

Conditions and interventions

Interventions

  • Lucitanib Drug
  • Nivolumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 28, 2019
Primary completion
Jun 30, 2023
Completion
Dec 31, 2023
Last update posted
Dec 19, 2022

2019 – 2024

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
12
Facility City State ZIP Site status
UCLA Jonsson Comprehensive Cancer Center Los Angeles California 90095
UC San Diego Moores Cancer Center San Diego California 92093
Anschutz Cancer Pavilion Aurora Colorado 80045
Florida Cancer Specialists Sarasota Florida 34232
Massachusetts General Hospital Boston Massachusetts 02114
NYU Langone Laura and Isaac Perlmutter Cancer Center New York New York 10016
Memorial Sloan Kettering Cancer Center New York New York 10065
Duke University School of Medicine Durham North Carolina 27710
Ohio State University Wexner Medical Center Columbus Ohio 43210
Stephenson Cancer Center Oklahoma City Oklahoma 73104
Magee-Womens Hospital of UPMC Pittsburgh Pennsylvania 15213
Tennessee Oncology Nashville Tennessee 37203
Swedish Cancer Institute Seattle Washington 98107

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04042116, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 19, 2022 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04042116 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →