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Completed Phase 2 Interventional Results available

Dexpramipexole Dose-Ranging Biomarker Study in Subjects With Eosinophilic Asthma

ClinicalTrials.gov ID: NCT04046939

Public ClinicalTrials.gov record NCT04046939. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 28, 2026, 11:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled Dose-Ranging Biomarker Study of the Effects of Dexpramipexole on Eosinophils in Subjects With Eosinophilic Asthma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a randomized, double-blind, placebo-controlled, parallel-group, dose-ranging, multi-center study to evaluate the clinical effects of oral administration of dexpramipexole for 12 weeks on peripheral blood eosinophil count in subjects with eosinophilic asthma.

Study identification

NCT ID
NCT04046939
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Knopp Biosciences
Industry
Enrollment
534 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 74 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 15, 2019 (Actual)
Primary completion
Dec 3, 2020 (Actual)
Completion
Mar 2, 2021 (Actual)
Last update posted
Apr 13, 2023

2019 – 2021

United States locations

U.S. sites
36
U.S. states
18
U.S. cities
33
Facility City State ZIP Site status
Research Site Los Angeles California 90048 —
Research Site Mission Viejo California 92691 —
Research Site Westminster California 92683 —
Research Site Denver Colorado 80230 —
Research Site Daytona Beach Florida 32117 —
Research Site Miami Florida 33186 —
Research Site Orlando Florida 32803 —
Research Site Tampa Florida 33612 —
Research Site Tampa Florida 33634 —
Research Site Lawrenceville Georgia 30046 —
Research Site Winder Georgia 30680 —
Research Site Boise Idaho 83706 —
Research Site Farmington Hills Michigan 48336 —
Research site Plymouth Minnesota 55441 —
Research Site St Louis Missouri 63110 —
Research Site St Louis Missouri 63141 —
Research Site Las Vegas Nevada 89119 —
Research Site New Brunswick New Jersey 08901 —
Research Site Corning New York 14830 —
Research Site New Hyde Park New York 11042 —
Research Site Raleigh North Carolina 27607 —
Research Site Winston-Salem North Carolina 27103 —
Research Site Cincinnati Ohio 45231 —
Research Site Cincinnati Ohio 45242 —
Research Site Columbus Ohio 43235 —
Research Site Dublin Ohio 43016 —
Research Site Edmond Oklahoma 73034 —
Research Site Medford Oregon 97504 —
Research Site Portland Oregon 97202 —
Research Site Pittsburgh Pennsylvania 15205 —
Research Site Anderson South Carolina 29621 —
Research Site North Charleston South Carolina 29406 —
Research Site Allen Texas 75013 —
Research Site Boerne Texas 78006 —
Research Site Dallas Texas 75240 —
Research Site El Paso Texas 79902 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04046939, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 13, 2023 · Synced Oct 28, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04046939 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →