Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis
Public ClinicalTrials.gov record NCT04048876. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Finding Study To Evaluate The Efficacy and Safety Of CC-90001 In Subjects With Non-Alcoholic Steatohepatitis (NASH) and Liver Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter, multinational, dose-finding study evaluating the efficacy of three treatment doses of CC-90001 compared with placebo, in Non-alcoholic Steatohepatitis (NASH) participants with Stage 2, Stage 3 liver fibrosis. This study is designed to assess response to treatment on measures of fibrosis and other efficacy parameters. It will also assess dose response and overall safety.
Study identification
- NCT ID
- NCT04048876
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 56 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 14, 2019 (Actual)
- Primary completion
- Sep 28, 2021 (Actual)
- Completion
- Sep 28, 2021 (Actual)
- Last update posted
- Jun 7, 2023
2019 – 2021
United States locations
- U.S. sites
- 64
- U.S. states
- 26
- U.S. cities
- 51
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saint Joseph's Hosptial and Medical Center - Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Mayo Clinic Phoenix | Phoenix | Arizona | 85054 | — |
| UC San Diego School of Medicine | La Jolla | California | 92093-0960 | — |
| Cedars-Sinai Comprehensive Transplant Center | Los Angeles | California | 90048 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| Inland Empire Liver Foundation | Rialto | California | 92377 | — |
| University of California Davis Medical Center | Sacramento | California | 95817 | — |
| Southern California GI & Liver Centers | San Clemente | California | 92673 | — |
| University of Colorado, School of Medicine - Hepatology Clinic - Anschutz | Aurora | Colorado | 80045 | — |
| Peak Gastroenterology Associates | Colorado Springs | Colorado | 80907 | — |
| South Denver Gastroenterology | Englewood | Colorado | 80113 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Yale Cancer Center | New Haven | Connecticut | 06520 | — |
| Florida Digestive Health Specialists | Lakewood Rch | Florida | 34202-2719 | — |
| Local Institution - 176 | Lakewood Rch | Florida | 34202-2719 | — |
| University of Miami Schiff Center for Liver Diseases | Miami | Florida | 33136 | — |
| IMIC, Inc. | Palmetto Bay | Florida | 33157 | — |
| Advanced Medical Research Center | Port Orange | Florida | 32127 | — |
| Tampa General Hospital | Tampa | Florida | 33606 | — |
| Gastrointestinal Specialists of Georgia, PC | Marietta | Georgia | 30060 | — |
| Rush University Medical Center - University Cardiovascular Surgeons | Chicago | Illinois | 60612 | — |
| University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| WestGlen Gastrointestinal Consultants, P.A. | Shawnee Mission | Kansas | 66217 | — |
| Tulane University Health Sciences Center | New Orleans | Louisiana | 70112 | — |
| Ochsner Medical Center | New Orleans | Louisiana | 70121 | — |
| The Institute for Digestive Health & Liver Disease at Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Digestive Disease Associates, PA | Catonsville | Maryland | 21228 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconness Medical Center | Boston | Massachusetts | 02215 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Saint Louis University School of Medicine | St Louis | Missouri | 63110-0250 | — |
| University of Nebraska | Omaha | Nebraska | 68198-7680 | — |
| Beth Israel Medical Center | New York | New York | 10003 | — |
| Concorde Medical Group | New York | New York | 10016 | — |
| New York Presbyterian Hospital - Weill-Cornell | New York | New York | 10021 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| Local Institution - 102 | Chapel Hill | North Carolina | 27514 | — |
| UNC Hospitals GI Medicine Clinic | Chapel Hill | North Carolina | 27514 | — |
| Duke University School of Medicine | Durham | North Carolina | 27710 | — |
| Carolinas HealthCare System Digestive Health | Huntersville | North Carolina | 28078 | — |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | — |
| University of Pittsburgh Medical Center - Center for Liver Diseases | Pittsburgh | Pennsylvania | 15213 | — |
| University Gastroenterology | Providence | Rhode Island | 02905 | — |
| ClinSearch LLC | Chattanooga | Tennessee | 37421 | — |
| Gastro One | Germantown | Tennessee | 38138 | — |
| Texas Clinical Research Institute LLC | Arlington | Texas | 76012 | — |
| Liver Institute at Methodist Dallas | Dallas | Texas | 75203 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Brooke Army Medical Center Francis Street Medical Center | Fort Sam Houston | Texas | 78235-8200 | — |
| Baylor College of Medicine - Baylor Heart Clinic | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Digestive Health Associates of Texas (DHAT) | Rockwell | Texas | 75032 | — |
| American Research Corporation | San Antonio | Texas | 78215 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| University of Vermont Medical Center Gastro | Burlington | Vermont | 05401 | — |
| Bon Secours Liver Institute of Hampton Roads | Newport News | Virginia | 23603 | — |
| Digestive and Liver Disease Specialists | Norfolk | Virginia | 23502 | — |
| Bon Secours Liver Institute of Richmond | Richmond | Virginia | 23226 | — |
| McGuire Veterans Affairs Medical Center | Richmond | Virginia | 23249 | — |
| Virginia Commonwealth University School of Medicine | Richmond | Virginia | 23298-0341 | — |
| University of Washington Harborview Medical Center | Seattle | Washington | 98104 | — |
| Liver Institute Northwest PLLC | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 78 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04048876, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 7, 2023 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04048876 live on ClinicalTrials.gov.