Impact of Bariatric Surgery on Pharmacokinetic Study of Simvastatin and Carvedilol
Public ClinicalTrials.gov record NCT04049786. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Impact of Roux-en-Y Gastric Bypass (RYGB) Bariatric Surgery on System Pharmacology: Single-dose Cross-over Pharmacokinetic Study of Simvastatin and Carvedilol.
Study identification
- NCT ID
- NCT04049786
- Recruitment status
- Not listed
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Natalia Valadares de Moraes
- Other
- Enrollment
- 120 participants
Conditions and interventions
Conditions
Interventions
- Carvedilol 25mg Drug
- Digestive biopsy Procedure
- Genotyping Other
- Metoprolol 100 mg for CYP2D6 phenotyping Drug
- Midazolam 2 mg for CYP3A4 phenotyping Drug
- Serial blood sampling for PK analysis Procedure
- Simvastatin 40mg Drug
Drug · Procedure · Other
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2019
- Primary completion
- Jul 31, 2022
- Completion
- Jul 31, 2023
- Last update posted
- Feb 7, 2022
2019 – 2023
United States locations
- U.S. sites
- 1
- U.S. states
- 1
- U.S. cities
- 1
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Florida | Orlando | Florida | 32827 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04049786, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 7, 2022 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04049786 live on ClinicalTrials.gov.