Safety and Tolerability of Cilofexor in Participants With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis
Public ClinicalTrials.gov record NCT04060147. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Proof-of-Concept, Open-Label Study Evaluating the Safety and Tolerability of Cilofexor in Subjects With Primary Sclerosing Cholangitis (PSC) and Compensated Cirrhosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to assess the safety and tolerability of escalating doses of cilofexor (CILO) in participants with primary sclerosing cholangitis (PSC) and compensated cirrhosis.
Study identification
- NCT ID
- NCT04060147
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 11 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 17, 2019 (Actual)
- Primary completion
- Sep 2, 2021 (Actual)
- Completion
- Sep 2, 2021 (Actual)
- Last update posted
- Jul 27, 2023
2019 – 2021
United States locations
- U.S. sites
- 16
- U.S. states
- 11
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Liver Health | Chandler | Arizona | 85224 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| University of California San Francisco, Liver Clinic | San Francisco | California | 94143 | — |
| Schiff Center for Liver Diseases/University of Miami | Miami | Florida | 33136 | — |
| Piedmont Atlanta Hospital | Atlanta | Georgia | 30309 | — |
| Indiana University Health University Hospital | Indianapolis | Indiana | 46202 | — |
| Louisiana Research Center, LLC | Shreveport | Louisiana | 71105 | — |
| Minnesota Gastroenterology, PA | Maplewood | Minnesota | 55117 | — |
| Northwell Health Center for Liver Diseases and Transplantation | Manhasset | New York | 11030 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| University of Virginia Medical Center | Charlottesville | Virginia | 22908 | — |
| Bon Secours Richmond Community Hospital, Inc. d/b/a Bon Secours Liver Institute of Richmond | Richmond | Virginia | 23226 | — |
| VCU Clinical Research Services Unit (CRSU) [Patient Site Address] | Richmond | Virginia | 23298 | — |
| University of Washington at Harborview Medical Center | Seattle | Washington | 98104 | — |
| Liver Institute Northwest | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04060147, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2023 · Synced Oct 29, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04060147 live on ClinicalTrials.gov.