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Completed Phase 1Phase 2 Interventional

Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib Patients With m-CRPC

ClinicalTrials.gov ID: NCT04060394

Public ClinicalTrials.gov record NCT04060394. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 2:37 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase I/II Dose-Escalation and Efficacy Study of LAE001/Prednisone Plus Afuresertib in Patients With Metastatic Castration-resistant Prostate Cancer Following Standard of Care Treatment

Study identification

NCT ID
NCT04060394
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Laekna Limited
Industry
Enrollment
49 participants

Conditions and interventions

Interventions

  • Phase I and Phase II: LAE001/prednisone + afuresertib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 12, 2019
Primary completion
Dec 26, 2023
Completion
Mar 29, 2024
Last update posted
Oct 9, 2024

2019 – 2024

United States locations

U.S. sites
12
U.S. states
11
U.S. cities
12
Facility City State ZIP Site status
Urological Associates of Southern Arizona Tucson Arizona 85741
California Cancer Associates for Researh & Excellence, Inc Encinitas California 92024
Eastern Connnecticut Hematology/Oncology Associates Norwich Connecticut 06360
Piedmont Columbus Regional Research Institute Columbus Georgia 31901
University of Chicago Chicago Illinois 60637
Cotton-O'Neil Clinical Research Center Topeka Kansas 66606
Associated Medical Professionals of NY Syracuse New York 13215
Oregon Urology Institute Florence Oregon 97439
Greenville Hospital System Greenville South Carolina 29605
Mary Crowley Cancer Research Centers Dallas Texas 75251
Baylor Scott and White Health Temple Texas 76508
Northwest Medical Specialties, PLLC Tacoma Washington 98405

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04060394, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 9, 2024 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04060394 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →