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Terminated Phase 3 Interventional Results available

Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease

ClinicalTrials.gov ID: NCT04064346

Public ClinicalTrials.gov record NCT04064346. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Study of the Efficacy and Safety of Lixivaptan in Participants With Autosomal Dominant Polycystic Kidney Disease Consisting of a 1-year Double-blind, Placebo-controlled, Randomized Phase and a 1-year Open-label Phase: The ACTION Study

Study identification

NCT ID
NCT04064346
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 3
Lead sponsor
Palladio Biosciences
Industry
Enrollment
12 participants

Conditions and interventions

Interventions

  • Lixivaptan Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 60 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 27, 2021
Primary completion
Aug 2, 2022
Completion
Aug 2, 2022
Last update posted
Feb 5, 2023

2021 – 2022

United States locations

U.S. sites
23
U.S. states
14
U.S. cities
23
Facility City State ZIP Site status
Nephrology Associates, PC - Greystone Hoover Alabama 35242
Nephrology Consultants, LLC Huntsville Alabama 35805-4104
Arizona Kidney Disease & Hypertension Center - Scottsdale / Pima Scottsdale Arizona 85258
JEM Research Institute Atlantis Florida 33462
Elixia at Florida Kidney Physicians - Southeast Fort Lauderdale Florida 33308
Qway Research Hialeah Florida 33010
South Florida Nephrology Associates PA Lauderdale Lakes Florida 33313-1600
Total Research Group, LLC Miami Florida 33126
Innovation Medical Research Center, Inc Palmetto Bay Florida 33157
Florida Kidney Physicians - Tampa Tampa Florida 33615
Clinical Site Partners, LLC Winter Park Florida 32789
Tufts Medical Center, Inc, Boston Massachusetts 02111
St Clair Nephrology Research, LLC Roseville Michigan 48066
Mayo Clinic Rochester Minnesota 55905
Clinical Research Consultants, LLC Kansas City Missouri 64111
Angel City Research, Inc Morrisville North Carolina 27560
Northeast Clinical Research Center, LLC Bethlehem Pennsylvania 18107
Brown Medicine - Brown Physicians Patient Center Riverside Rhode Island 02915-2235
Knoxville Kidney Center LLC Knoxville Tennessee 37923
Prolato Clinical Research Center (PCRC) Houston Texas 77054-2854
Clinical Advancement Center, PLLC San Antonio Texas 78212
Utah Kidney Research Institute Salt Lake City Utah 84115
Nephrology Associates of Northern Virginia, Inc Fairfax Virginia 22033

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04064346, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 5, 2023 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04064346 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →