Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis.
Public ClinicalTrials.gov record NCT04065841. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Parallel-group, Multicenter Study to Assess Efficacy, Safety, and Tolerability of Oral Tropifexor (LJN452) & Licogliflozin (LIK066) Combination Therapy and Each Monotherapy, Compared With Placebo for Treatment of Adult Patients With Nonalcoholic Steatohepatitis (NASH) and Liver Fibrosis.(ELIVATE)
Study identification
- NCT ID
- NCT04065841
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 234 participants
Conditions and interventions
Conditions
Interventions
- Tropifexor Drug
- Licogliflozin Drug
- Placebo Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 29, 2019
- Primary completion
- Oct 26, 2022
- Completion
- Oct 26, 2022
- Last update posted
- Jan 27, 2025
2019 – 2022
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Gut PC Digestive Health Specialist | Dothan | Alabama | 36305 | — |
| Southern California Research Center | Coronado | California | 92118 | — |
| Velocity Clinical Trials | Los Angeles | California | 90057 | — |
| California Liver Research Institute | Pasadena | California | 91105 | — |
| Medical Associates Research Group | San Diego | California | 92123 | — |
| San fernando Valley Health Institute | Van Nuys | California | 91405 | — |
| Island View Gastroenterology Associates | Ventura | California | 93003 | — |
| Integrity Clinical Rsh LLC | Doral | Florida | 33166 | — |
| Galenus Group | Lehigh Acres | Florida | 33936 | — |
| Genoma Research Group Inc | Miami | Florida | 33165-7574 | — |
| Digestive Res Alliance of Michiana | South Bend | Indiana | 46635 | — |
| Southern Therapy and Adv Res LLC | Jackson | Mississippi | 39216 | — |
| Clinical Research Professionals Inc | Chesterfield | Missouri | 63005 | — |
| Southwest Gastroenterology Associates | Albuquerque | New Mexico | 87109 | — |
| Northwell Health | Manhasset | New York | 11030 | — |
| Clinical Trials Of America LLC | Lenoir | North Carolina | 28645 | — |
| Diabetes And Endocrinology Conslt | Morehead City | North Carolina | 28557 | — |
| Options Health Research | Tulsa | Oklahoma | 74104 | — |
| Prisma Health | Greenville | South Carolina | 29605 | — |
| Digestive Disease Research | Greenwood | South Carolina | 29646 | — |
| Palmetto Clinical Research | Summerville | South Carolina | 29485 | — |
| Summit Medical Care | Hermitage | Tennessee | 37076 | — |
| Texas Clinical Research Institute | Arlington | Texas | 76012 | — |
| Dallas Diabetes and Endocrine Center | Dallas | Texas | 75230 | — |
| American Research Corporation at Texas Liver Institute | San Antonio | Texas | 78215 | — |
| Clinical Trials of Texas | San Antonio | Texas | 78229 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Pioneer Research Solutions | Sugar Land | Texas | 77479 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04065841, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 27, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04065841 live on ClinicalTrials.gov.