Treg Modulation With CD28 and IL-6 Receptor Antagonists
Public ClinicalTrials.gov record NCT04066114. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Regulatory T Cell Modulation in Kidney Transplantation With Biologic Blockade of Dual Effector Pathways, CD28 and IL-6 (CTOT-24)
Study identification
- NCT ID
- NCT04066114
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 24 participants
Conditions and interventions
Interventions
- Prednisone Drug
- antithymocyte globulin (rabbit) Biological
- belatacept Biological
- everolimus Drug
- lulizumab pegol Biological
- methylprednisolone Drug
- mycophenolate mofetil Drug
- mycophenolic acid Drug
- tocilizumab Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 10, 2019
- Primary completion
- Sep 13, 2023
- Completion
- Sep 13, 2023
- Last update posted
- Oct 8, 2024
2019 – 2023
United States locations
- U.S. sites
- 7
- U.S. states
- 7
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama School of Medicine: Transplantation | Birmingham | Alabama | 35233 | — |
| University of California San Francisco School of Medicine: Transplantation | San Francisco | California | 94143 | — |
| University of Colorado (UC) Health Transplant Center - Anschutz | Aurora | Colorado | 80045 | — |
| Northwestern Memorial Hospital: Transplantation | Chicago | Illinois | 60611 | — |
| University of Nebraska Medical Center: Transplantation | Omaha | Nebraska | 68105 | — |
| Duke University Medical Center: Transplantation | Durham | North Carolina | 27710 | — |
| Cleveland Clinic Foundation: Transplantation | Cleveland | Ohio | 44195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04066114, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 8, 2024 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04066114 live on ClinicalTrials.gov.