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Completed Phase 1Phase 2 Interventional

SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients

ClinicalTrials.gov ID: NCT04067115

Public ClinicalTrials.gov record NCT04067115. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination With Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging

Study identification

NCT ID
NCT04067115
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Sarcoma Alliance for Research through Collaboration
Other
Enrollment
37 participants

Conditions and interventions

Conditions

Interventions

  • 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging Other
  • Irinotecan Drug
  • Trabectedin 1 MG [Yondelis] Drug
  • tumor biopsy Diagnostic Test

Other · Drug · Diagnostic Test

Eligibility (public fields only)

Age range
6 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 4, 2021
Primary completion
Apr 23, 2025
Completion
Apr 23, 2025
Last update posted
Dec 16, 2025

2021 – 2025

United States locations

U.S. sites
6
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
Children's Hospital of Los Angeles Los Angeles California 90027
National Cancer Institute Bethesda Maryland 20892
Boston Children's Hospital / Dana Farber Cancer Institute Boston Massachusetts 02215
University of Michigan Ann Arbor Michigan 48106
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
University of Pennsylvania Philadelphia Pennsylvania 19105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04067115, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 16, 2025 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04067115 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →