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Completed Phase 2 Interventional Results available

PTI-125 for Mild-to-moderate Alzheimer's Disease Patients

ClinicalTrials.gov ID: NCT04079803

Public ClinicalTrials.gov record NCT04079803. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 22, 2026, 10:45 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b, Randomized, Double-blind, Placebo-controlled, Multiple Dose, Biomarker and Safety Study of PTI-125 in Mild-to-moderate Alzheimer's Disease Patients

Study identification

NCT ID
NCT04079803
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cassava Sciences, Inc.
Industry
Enrollment
64 participants

Conditions and interventions

Interventions

  • Placebo oral tablet Drug
  • Simufilam 100 mg tablet Drug
  • Simufilam 50 mg oral tablet Drug

Drug

Eligibility (public fields only)

Age range
50 Years to 85 Years
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 8, 2019
Primary completion
Mar 30, 2020
Completion
Mar 30, 2020
Last update posted
Sep 28, 2021

2019 – 2020

United States locations

U.S. sites
9
U.S. states
5
U.S. cities
9
Facility City State ZIP Site status
Cognitive Clinical Trials Gilbert Arizona 85296
Cognitive Clinical Trials Surprise Arizona 85374
Optimus U Miami Florida 33125
IMIC, Inc. Palmetto Bay Florida 33157
Cognitive Clinical Trials Bellevue Nebraska 68005
Cognitive Clinical Trials Omaha Nebraska 68116
Advanced Memory Research Institute Toms River New Jersey 08755
Centex Studies, Inc. Houston Texas 77058
Centex Studies, Inc. McAllen Texas 78504

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04079803, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2021 · Synced Apr 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04079803 live on ClinicalTrials.gov.

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