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Active, not recruiting Phase 1Phase 2 Interventional

IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia

ClinicalTrials.gov ID: NCT04086264

Public ClinicalTrials.gov record NCT04086264. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 3:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2 Study of IMGN632 as Monotherapy or Combination With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia

Study identification

NCT ID
NCT04086264
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
218 participants

Conditions and interventions

Interventions

  • Azacitidine Drug
  • IMGN632 Drug
  • Venetoclax Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 5, 2019
Primary completion
Jan 31, 2027
Completion
Jan 31, 2027
Last update posted
Aug 13, 2025

2019 – 2027

United States locations

U.S. sites
13
U.S. states
11
U.S. cities
13
Facility City State ZIP Site status
City of Hope National Medical Center /ID# 269273 Duarte California 91010
University Of California Irvine Medical Center /ID# 269275 Orange California 92868
Moffitt Cancer Center /ID# 269269 Tampa Florida 33612
Northwestern University- Robert H. Lurie Comprehensive Cancer Center /ID# 269642 Chicago Illinois 60611-3015
Dana-Farber Cancer Institute /ID# 269267 Boston Massachusetts 02215
University of Michigan /ID# 269079 Ann Arbor Michigan 48109-2800
Mayo Clinic Hospital Rochester /ID# 269643 Rochester Minnesota 55905
Roswell Park Cancer Institute /ID# 269266 Buffalo New York 14263
New York Presbyterian Hospital Weill Cornell Medical Center /ID# 269271 New York New York 10461
Duke University Health System /ID# 269268 Durham North Carolina 27705-3976
Cleveland Clinic - Cleveland /ID# 269272 Cleveland Ohio 44195
MD Anderson Houston /ID# 269265 Houston Texas 77030-4000
Fred Hutchinson Cancer Research Center /ID# 269270 Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04086264, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 13, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04086264 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →