Study of TAK-925 in Participants With Obstructive Sleep Apnea (OSA) Who Are Experiencing Excessive Daytime Sleepiness (EDS) Despite Adequate Use of Continuous Positive Airway Pressure (CPAP)

ClinicalTrials.gov ID: NCT04091425

Public ClinicalTrials.gov record NCT04091425. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b Randomized, Double-blind, Placebo-Controlled, Crossover Study of 2 Single Intravenous Infusion Doses of TAK-925 in Subjects With Obstructive Sleep Apnea Who Are Experiencing Excessive Daytime Sleepiness Despite Adequate Use of CPAP

Study identification

NCT ID: NCT04091425
Recruitment status: Completed
Study type: Interventional
Phase: Phase 1
Lead sponsor: Millennium Pharmaceuticals, Inc.; Industry
Enrollment: 25 participants

Conditions and interventions

Conditions

Obstructive Sleep Apnea

Interventions

TAK-925 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 67 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 20, 2019
Primary completion: Apr 1, 2020
Completion: Apr 1, 2020
Last update posted: Apr 19, 2020

2019 – 2020

United States locations

U.S. sites: 18
U.S. states: 11
U.S. cities: 18

Facility	City	State	ZIP	Site status
Wright Clinical Research	Alabaster	Alabama	35007	—
Pulmonary Associates Clinical Trials	Glendale	Arizona	85306	—
Preferred Research Partners, Inc.	Little Rock	Arkansas	72211	—
Stanford School of Medicine	Redwood City	California	94063	—
Pacific Research Network, Inc	San Diego	California	92103	—
Delta Waves Sleep Disorders and Research Center	Colorado Springs	Colorado	80918	—
MD Clinical	Hallandale	Florida	33009	—
Research Centers of America	Hollywood	Florida	33024	—
Jacksonville Center for Clinical Research	Jacksonville	Florida	32216	—
Pulmonary Disease Specialists, PA, d/b/a PDS Research	Kissimmee	Florida	34741	—
Florida Pulmonary Research Institute, LLC	Winter Park	Florida	32789	—
NeuroTrials Research, Inc.	Atlanta	Georgia	30342	—
SleepCare Research Institute, Inc. d/b/a Clinical Research Institute	Stockbridge	Georgia	30281	—
Helene A. Emsellem, MD PC trading as "The Center for Sleep & Wake Disorders"	Chevy Chase	Maryland	20815	—
CTI Clinical Trial and Consulting Services	Cincinnati	Ohio	45212	—
The Cleveland Clinic Foundation	Cleveland	Ohio	44195	—
Bogan Sleep Consultants, LLC	Columbia	South Carolina	29201	—
Sleep Therapy & Research Center	San Antonio	Texas	78229	—

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04091425, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 19, 2020 · Synced Jul 21, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04091425 live on ClinicalTrials.gov.

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