A Study to Evaluate the Safety and Efficacy of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa
Public ClinicalTrials.gov record NCT04092452. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 2A, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 16-WEEK STUDY EVALUATING THE SAFETY AND EFFICACY OF PF-06650833, PF-06700841, AND PF-06826647 IN ADULTS WITH MODERATE TO SEVERE HIDRADENITIS SUPPURATIVA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study with 3 kinase inhibitors (PF 06650833, PF 06700841 and PF 06826647) in participants with moderate to severe HS. The study will have a maximum duration of approximately 26 weeks. This includes an up to 6-week Screening Period, a 16 week Dosing Period and a 4 week Follow up Period.
Study identification
- NCT ID
- NCT04092452
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 194 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 2, 2019 (Actual)
- Primary completion
- Jan 10, 2022 (Actual)
- Completion
- Jan 10, 2022 (Actual)
- Last update posted
- Jun 15, 2023
2019 – 2022
United States locations
- U.S. sites
- 63
- U.S. states
- 23
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University Of Alabama At Birmingham | Birmingham | Alabama | 35233 | — |
| The University of Alabama at Birmingham Hospital Outreach Lab | Birmingham | Alabama | 35249 | — |
| The University of Alabama at Birmingham Investigation Drug Services Pharmacy | Birmingham | Alabama | 35249 | — |
| The University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Mayo Clinic | Scottsdale | Arizona | 85259 | — |
| Center for Dermatology Clinical Research, Inc. | Fremont | California | 94538 | — |
| Pacific Clinical Trials | Long Beach | California | 90806 | — |
| Keck School of Medicine of University of Southern California | Los Angeles | California | 90033 | — |
| UCSF Dermatology Clinic | San Francisco | California | 94115 | — |
| University of California San Francisco | San Francisco | California | 94115 | — |
| UCSF Psoriasis and Skin Treatment Center | San Francisco | California | 94118 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| New England Research Associates, LLC | Bridgeport | Connecticut | 06606 | — |
| Dermatology Physicians of Connecticut | Shelton | Connecticut | 06484 | — |
| Total Dermatology Care Center | Jacksonville | Florida | 32204 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Olympian Clinical Research Largo Office | Largo | Florida | 33770 | — |
| University of Miami Hospital | Miami | Florida | 33125 | — |
| Tory Sullivan MD PA | North Miami Beach | Florida | 33162 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| MidState Skin Institute | Ocala | Florida | 34471 | — |
| Renstar Medical Research | Ocala | Florida | 34471 | — |
| Park Avenue Dermatology | Orange Park | Florida | 32073 | — |
| Leavitt Medical Associates of Florida d/b/a Ameriderm Research | Ormond Beach | Florida | 32174 | — |
| Riverchase Dermatology and Cosmetic Surgery | Pembroke Pines | Florida | 33028 | — |
| ForCare Clinical Research | Tampa | Florida | 33613 | — |
| Alliance Clinical Research of Tampa | Tampa | Florida | 33615 | — |
| MedaPhase Inc. | Newnan | Georgia | 30263 | — |
| Advanced Medical Research PC | Sandy Springs | Georgia | 30328 | — |
| Georgia Skin Cancer and Aesthetic Dermatology | Watkinsville | Georgia | 30677 | — |
| NorthShore University HealthSystem Dermatology Clinic | Skokie | Illinois | 60077 | — |
| Ds Research | Clarksville | Indiana | 47129 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| DS Research | Louisville | Kentucky | 40241 | — |
| Boston Medical Center | Boston | Massachusetts | 02118 | — |
| Boston University General Clinical Research Unit | Boston | Massachusetts | 02118 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| Wayne State University / Integrative Biosciences Center | Detroit | Michigan | 48202 | — |
| Revival Research Institute, LLC | Troy | Michigan | 48084 | — |
| Clinical Research Unit | Minneapolis | Minnesota | 55455 | — |
| Lillihei Clinical Research Unit | Minneapolis | Minnesota | 55455 | — |
| University of Minnesota Department of Dermatology | Minneapolis | Minnesota | 55455 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Saint Louis University - Department of Dermatology | St Louis | Missouri | 63110 | — |
| Skin Specialists PC | Omaha | Nebraska | 68144 | — |
| J Woodson Clinical Studies Group | Henderson | Nevada | 89052 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Vital Prospects Clinical Research Institute | Tulsa | Oklahoma | 74136 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Penn State Health Radiology - University Physician Center | Hershey | Pennsylvania | 17033 | — |
| Paddington Testing Company, Inc | Philadelphia | Pennsylvania | 19103 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Dermatology and Skin Cancer Consultants | Humboldt | Tennessee | 38343 | — |
| Clinical Research Solutions | Jackson | Tennessee | 38305 | — |
| Dermatology and Skin Cancer Consultants | Jackson | Tennessee | 38305 | — |
| Arlington Research Center | Arlington | Texas | 76011 | — |
| Austin Institute for Clinical Research, Inc. | Pflugerville | Texas | 78660 | — |
| University of Utah MidValley Dermatology | Murray | Utah | 84107 | — |
| Virginia Commonwealth University Medical Center | Richmond | Virginia | 23298 | — |
| Bellevue Dermatology Clinical Research Center | Bellevue | Washington | 98004 | — |
| Bellevue Dermatology Clinic | Bellevue | Washington | 98004 | — |
| Dermatology Associates of Seattle | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04092452, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 15, 2023 · Synced Oct 28, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04092452 live on ClinicalTrials.gov.