A Study for Participants Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Public ClinicalTrials.gov record NCT04093570. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Multicenter, Extension Study for Subjects Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Extension study to provide ongoing long-term treatment with ASTX727 for participants who were benefitting from ASTX727 treatment in a previous Taiho (formerly Astex)-sponsored clinical study of ASTX727 (including, but not limited to ASTX727-01 \[NCT02103478\], ASTX727-02 \[NCT03306264\], ASTX727-04 \[NCT03813186\]), ASTX727-06 \[NCT04093570\] food effect substudy, ASTX727-17 \[NCT04953897\], and ASTX727-18 \[NCT04953910\] to obtain long-term safety information. The purpose of the Food Effect Substudy was to evaluate the pharmacokinetics (PK) and safety of decitabine and cedazuridine when ASTX727 was given under fed (high-calorie/high-fat meal or low-calorie/low-fat meal) versus fasted conditions. Food Effect Substudy has now completed.
Study identification
- NCT ID
- NCT04093570
- Recruitment status
- Enrolling by invitation
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 332 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 30, 2019 (Actual)
- Primary completion
- Dec 31, 2027 (Estimated)
- Completion
- Dec 31, 2027 (Estimated)
- Last update posted
- Jul 28, 2026
2019 – 2027
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Compassionate Care Research Group | Fountain Valley | California | 92708 | — |
| Boca Raton Clinical Research | Plantation | Florida | 33322 | — |
| The University of Chicago Medical Center | Chicago | Illinois | 60637 | — |
| The Sidney Kimmel Comprehensive Cancer Center at John Hopkins | Baltimore | Maryland | 21231 | — |
| Cancer and Hematology Centers for Western Michigan | Grand Rapids | Michigan | 49503 | — |
| Mayo - Rochester | Rochester | Minnesota | 55905 | — |
| Hackensack Medical Center - 06 FE Study | Hackensack | New Jersey | 07601 | — |
| Hackensack Medical Center | Hackensack | New Jersey | 07601 | — |
| Rosewell Park Cancer Institute | Buffalo | New York | 14263 | — |
| Roswell Park Cancer Institute - 06 FE Study | Buffalo | New York | 14263 | — |
| Gabrail Cancer Center Research - 06 FE Study | Canton | Ohio | 44718 | — |
| Gabrail Cancer Center Research | Canton | Ohio | 44718 | — |
| Oregon Health and Science University | Portland | Oregon | 92739 | — |
| Charleston Hematology Oncology Associates | Charleston | South Carolina | 29414 | — |
| Vanderbilt - Ingram Cancer Center | Nashville | Tennessee | 37232 | — |
| Baylor Scott White University Medical Center | Dallas | Texas | 75246 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| May Cancer Center | San Antonio | Texas | 78229 | — |
| Kadlec Clinic Hematology and Oncology | Kennewick | Washington | 99336 | — |
| Seattle Cancer Care Alliance/Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04093570, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 28, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04093570 live on ClinicalTrials.gov.